Functional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies for host adaptation and persistence [PDF]
, 2016 Background: Mycobacterium abscessus subsp. abscessus (MAB) is a highly drug resistant mycobacterium and the most common respiratory pathogen among the rapidly growing non-tuberculous mycobacteria. MAB is also one of the most deadly of the emerging cystic
Dinan, Adam M. +4 more
core +2 more sources
Epetraborole Is Active against Mycobacterium abscessus
Antimicrobial Agents and Chemotherapy, 2021 Benzoxaboroles are a new class of leucyl-tRNA synthetase inhibitors. We recently reported that the antitubercular 4-halogenated benzoxaboroles are active against Mycobacterium abscessus .
Uday S. Ganapathy +2 more
openaire +2 more sources
International Journal of Infectious Diseases, 2017 Objectives: The differentiation between Mycobacterium abscessus subspecies abscessus (M. abscessus) and Mycobacterium abscessus subspecies massiliense (M. massiliense) and determination of the presence of inducible resistance to macrolide antibiotics are
Suk Hyeon Jeong +9 more
doaj +1 more source
Pathogen Box screening for hit identification against Mycobacterium abscessus. [PDF]
PLoS ONE, 2018 Mycobacterium abscessus is a rapidly growing life-threatening mycobacterium with multiple drug-resistance mechanisms. However, there is no official regimen for M. abscessus therapy.
Jinsun Jeong +5 more
doaj +1 more source
Microbiology Spectrum, 2023 Mycobacterium abscessus, an intracellular nontuberculous mycobacterium, is considered the most pathogenic species among the group of rapidly growing mycobacteria. The resistance of M. abscessus to the host innate response contributes to its pathogenicity
Hamadoun Touré +5 more
doaj +1 more source
Aggregation of nontuberculous mycobacteria is regulated by carbon-nitrogen balance [PDF]
, 2019 Nontuberculous mycobacteria (NTM) are emerging opportunistic pathogens that colonize household water systems and cause chronic lung infections in susceptible patients.
Aanderud +81 more
core +3 more sources
atpE gene as a new useful specific molecular target to quantify Mycobacterium in environmental samples [PDF]
, 2013 International audienceBackgroundThe environment is the likely source of many pathogenic mycobacterial species but detection of mycobacteria by bacteriological tools is generally difficult and time-consuming.
Accrombessi, Héberte +8 more
core +7 more sources
General Overview on Nontuberculous Mycobacteria, Biofilms, and Human Infection [PDF]
, 2015 Nontuberculous mycobacteria (NTM) are emergent pathogens whose importance in human health has been growing. After being regarded mainly as etiological agents of opportunist infections in HIV patients, they have also been recognized as etiological agents ...
Faria, Sónia +2 more
core +4 more sources
Culture-independent detection of nontuberculous mycobacteria in clinical respiratory samples [PDF]
, 2016 Culture-based detection of nontuberculous Mycobacteria (NTM) in respiratory samples is time consuming and can be subject to overgrowth by nonmycobacterial bacteria.
Bastian, Ivan +8 more
core +1 more source
Mycobacterium abscessus Pneumonia in Severe Alcoholism
Cureus, 2022 Non-tuberculous mycobacterial infections (mycobacterium other than Mycobacterium tuberculosis and Mycobacterium leprae) are organisms that are commonly found in the environment such as water, soil, and dust. They may form difficult to eliminate biofilms and have been reported to cause significant infections in humans, especially in immunocompromised ...
Acharya, Sudeep +4 more
openaire +2 more sources