Schematic representation of the research workflow for the efficient diagnosis of bovine tuberculosis employing peptide fusion proteins. ABSTRACT Bovine tuberculosis (bTB) diagnostics are frequently hindered by the structural instability and insolubility of recombinant multi‐epitope proteins in prokaryotic expression systems.
Wen‐Hao Wang +15 more
wiley +1 more source
Mycobacterium avium subsp. paratuberculosis in Colombia (1924-2016): A review
Mycobacterium avium subsp. paratuberculosis (MAP) is an acid-fast, gram-positive bacillus. MAP is the causal agent of paratuberculosis (PTB) or Johne’s disease, an infectious disease affecting domestic ruminants and some wild species. Its importance as a potentially zoonotic agent due to its relation to Crohn’s disease (CD) in humans is still under ...
Correa Valencia, Nathalia María del Pilar +2 more
openaire +5 more sources
Effective control of Johne’s disease in large Czech dairy herds
Johne’s disease, caused by infection with Mycobacterium avium subsp. paratuberculosis (MAP), causes economic losses in dairy herds due to reduced milk production and premature culling.
Fichtelová Věra +3 more
doaj +1 more source
The Relationship Between Immunopathology and Body Condition of Mixed‐Age Ewes
Ill thrift in ewes, characterised by less than desirable body condition, is a multifactorial condition often attributed to nutritional deficits, though immunopathological factors may also play a role. This study investigated associations between body condition scores (BCS) and immunopathological states in 120 mixed‐age ewes grazing pasture over 4 ...
Melissa N. Hempstead +15 more
wiley +1 more source
Enzyme-linked immunospot: an alternative method for the detection of interferon gamma in Johne's disease [PDF]
. To date, the sensitivity of the interferon gamma (IFN-c) enzyme-linked immunosorbent assay (ELISA) to detect Johne’s disease (JD) has been poor, especially in the early stages of disease.
Begg, Douglas J. +6 more
core +2 more sources
ABSTRACT Mycobacteriophage Mcgavigan could be a promising candidate for use as a preventative agent against infections with Mycobacterium avium subsp. paratuberculosis. Bioinformatic analysis of the Mcgavigan genome revealed the presence of an operon containing a “Bxb1‐like” repressor.
Natali Shafer +2 more
wiley +1 more source
Specific immunoassays confirm association of Mycobacterium avium subsp. paratuberculosis with type-1 but not type-2 diabetes mellitus [PDF]
Background Mycobacterium avium subspecies paratuberculosis (MAP) is a versatile pathogen with a broad host range. Its association with type-1 diabetes mellitus (T1DM) has been recently proposed.
Ahmed, Niyaz +7 more
core
Comparative analysis of subsp. isolates from cattle, sheep and goats by short sequence repeat and pulsed-field gel electrophoresis typing [PDF]
Background Mycobacterium avium subsp. paratuberculosis (Map) causes the chronic enteritis called paratuberculosis mainly in cattle, sheep and goats. Evidences that point out an association between Map and Crohn's Disease in humans are increasing.
Kapur Vivek +6 more
core +1 more source
Epigenetic Modifications Influence Reproductive Traits in Small Ruminants
The epigenome undergoes dynamic changes shaped by the intricate interplay of genetic and environmental factors, which are crucial for individual growth and development. Recent studies suggest that factors such as nutrition, thermal stress (TS), infections, and assisted reproductive technologies (ARTs) can influence epigenetic changes in small ruminants
Galma Boneya Arero +2 more
wiley +1 more source
ДИФЕРЕНЦИРАНЕ НА ВИДОВЕ МИКОБАКТЕРИИ ОТ MYCOBACTERIUM AVIUM COMPLEX
Mycobacterium avium complex (МАС) включва M. avium, M. paratuberculosis, M. lepraemurium и M. intracellulare. Mycobacterium avium subsp. avium (МАА) и М. avium subsp.
Таня Савова +3 more
doaj

