Results 21 to 30 of about 6,385 (210)

Killing of Mycobacterium avium subspecies paratuberculosis within macrophages [PDF]

BMC Microbiology, 2002
Mycobacterium avium subspecies paratuberculosis (M. paratuberculosis) is a facultative intracellular pathogen that resides within host macrophages during infection of ruminant animals. We examined survival of M. paratuberculosis infections within cultured macrophages to better understand the interplay between bacterium and host.Serial plating of M ...
Bannantine, John P., Stabel, Judith R.
openaire   +3 more sources

Diagnostic Sequences That Distinguish M. avium Subspecies Strains

Frontiers in Veterinary Science, 2021
Over a decade ago Mycobacterium avium subspecies paratuberculosis (Map) specific genes were initially identified in a whole genome context by comparing draft genome sequences of Map strain K-10 with Mycobacterium avium subspecies hominissuis (Mah) strain
John P. Bannantine, Judith R. Stabel, Darrell O. Bayles, Cyril Conde, Franck Biet   +4 more
doaj   +1 more source

Genetic Features of Mycobacterium avium subsp. paratuberculosis Strains Circulating in the West of France Deciphered by Whole-Genome Sequencing

Microbiology Spectrum, 2022
Paratuberculosis is a chronic infection of the intestine, mainly the ileum, caused by Mycobacterium avium subsp. paratuberculosis in cattle and other ruminants.
Cyril Conde, Julien Thézé, Thierry Cochard, Marie-Noëlle Rossignol, Christine Fourichon, Arnaud Delafosse, Alain Joly, Raphael Guatteo, Laurent Schibler, John P. Bannantine, Franck Biet   +10 more
doaj   +1 more source

Mycobacterium avium subspecies paratuberculosis: A possible causative agent in human morbidity and risk to public health safety [PDF]

Open Veterinary Journal, 2018
Mycobacterium avium subspecies paratuberculosis is a bacterial parasite and the causative agent of paratuberculosis, a disease predominately found in cattle and sheep.
Mary Garvey
doaj   +1 more source

Novel single nucleotide polymorphism-based assay for genotyping Mycobacterium avium subsp. paratuberculosis [PDF]

, 2016
Typing of Mycobacterium avium subspecies paratuberculosis strains presents a challenge, since they are genetically monomorphic and traditional molecular techniques have limited discriminatory power.
Bryant, Josephine, Goldstone, Robert J., Inácio, João, Leão, Célia, McLuckie, Joyce, Smith, David G.E., Stevenson, Karen   +6 more
core   +2 more sources

Optical mapping of the Mycobacterium avium subspecies paratuberculosis genome [PDF]

BMC Genomics, 2009
Abstract Background Infection of cattle with Mycobacterium avium subspecies paratuberculosis (M. ap) causes severe economic losses to the dairy industry in the USA and worldwide. In an effort to better examine diversity among M. ap strains, we used optical mapping to profile genomic variations between strains of M. ap
Schwartz David C, Zhou Shiguo, Schramm Timothy M, Wu Chia-wei, Talaat Adel M   +4 more
openaire   +3 more sources

The Effect of Mycobacterium avium subsp. Paratuberculosis Infection on the Productivity of Cows in Two Dairy Herds with a Low Seroprevalence of Paratuberculosis

Animals, 2020
Paratuberculosis is a chronic, progressive enteritis of ruminants, caused by Mycobacterium avium subspecies paratuberculosis. It affects the productivity of infected dairy cows, causing a reduction in the daily milk yield and basic milk components.
Agnieszka Wiszniewska-Łaszczych, Katarzyna G. Liedtke, Joanna M. Szteyn, Tomasz Lachowicz   +3 more
doaj   +1 more source

Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

Vaccines, 2021
Heterologous prime-boost strategies are known to substantially increase immune responses in viral vectored vaccines. Here we report on safety and immunogenicity of the poxvirus Modified Vaccinia Ankara (MVA) vectored vaccine expressing four Mycobacterium
Pedro M. Folegatti, Amy Flaxman, Daniel Jenkin, Rebecca Makinson, Lucy Kingham-Page, Duncan Bellamy, Fernando Ramos Lopez, Jonathan Sheridan, Ian Poulton, Jeremy Aboagye, Nguyen Tran, Celia Mitton, Rachel Roberts, Alison M. Lawrie, Adrian V. S. Hill, Katie J. Ewer, Sarah Gilbert   +16 more
doaj   +1 more source

Genetic Diversity Among Mycobacterium avium Subspecies Revealed by Analysis of Complete Genome Sequences

Frontiers in Microbiology, 2020
Mycobacterium avium comprises four subspecies that contain both human and veterinary pathogens. At the inception of this study, twenty-eight M. avium genomes had been annotated as RefSeq genomes, facilitating direct comparisons.
John P. Bannantine, Cyril Conde, Darrell O. Bayles, Maxime Branger, Franck Biet   +4 more
doaj   +1 more source

Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains [PDF]

, 2013
BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks
Bull, TJ, Greene, M, Linedale, R, McKendrick, IJ, Sales, J, Schock, A, Sharp, JM, Stevenson, K   +7 more
core   +1 more source