Results 31 to 40 of about 2,057 (131)

Comparative Transcriptomic Analysis of Human Macrophages During Mycobacterium avium Versus Mycobacterium tuberculosis Infection

Molecular Microbiology, Volume 125, Issue 3, Page 185-202, March 2026.
Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç, Robin H. G. A. van den Biggelaar, Tom H. M. Ottenhoff, Leon H. Mei, Anno Saris   +4 more
wiley   +1 more source

The Effect of Mycobacterium avium Complex Infections on Routine Mycobacterium bovis Diagnostic Tests

Veterinary Medicine International, 2011
Bovine tuberculosis (bTB) is diagnosed in naturally infected populations exposed to a wide variety of other pathogens. This study describes the cell-mediated immune responses of cattle exposed to Mycobacterium avium subspecies paratuberculosis (Map) and ...
Claire Barry, David Corbett, Douwe Bakker, Peter Andersen, Jim McNair, Sam Strain   +5 more
doaj   +1 more source

The Relationship Between Immunopathology and Body Condition of Mixed‐Age Ewes

New Zealand Journal of Agricultural Research, Volume 69, Issue 1, February 2026.
Ill thrift in ewes, characterised by less than desirable body condition, is a multifactorial condition often attributed to nutritional deficits, though immunopathological factors may also play a role. This study investigated associations between body condition scores (BCS) and immunopathological states in 120 mixed‐age ewes grazing pasture over 4 ...
Melissa N. Hempstead, Sandeep K. Gupta, Paul M. Candy, Rina Hannaford, Dave M. Leathwick, Chris M. Miller, Anne L. Ridler, Mallory A. Ross, Laura B. Hunter, Trevor J. Watson, Tania A. Wilson, Karin E. Schütz, Alex K. Chambers, Christian W. Sauermann, Cheryl E. O’Connor, Natalie A. Parlane   +15 more
wiley   +1 more source

Genome-wide sequence variations among Mycobacterium avium subspecies paratuberculosis.

Frontiers in Microbiology, 2011
Mycobacterium avium subspecies paratuberculosis (M. ap), the causative agent of Johne’s disease (JD), infects many farmed ruminants, wildlife animals and humans.
Chung-Yi eHsu, Chia-wei eWu, Adel M Talaat   +2 more
doaj   +1 more source

Specificity Evaluation of a Polyprotein‐Based ELISA Designed for the Detection of Paratuberculosis in Multiple Species

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Paratuberculosis (PTB) is a disease affecting ruminant animals. The etiological agent, Mycobacterium avium subspecies PTB (Map), is a short, Gram‐positive, acid‐fast bacillus. Due to the nature of PTB, diagnosis often occurs at advanced stages of the disease, following the onset of clinical symptoms and prior dissemination of the agent. The specificity
R. D. Moyano, M. A. Colombatti Olivieri, M. Basconez González, J. M. Garrido, R. A. Juste, M. N. Alonso, Juan Pablo Damián   +6 more
wiley   +1 more source

High clonality of Mycobacterium avium subsp. paratuberculosis field isolates from red deer revealed by two different methodological approaches of comparative genomic analysis

Frontiers in Veterinary Science
Mycobacterium avium subsp. paratuberculosis (MAP) is the aetiological agent of paratuberculosis (Johne’s disease) in both domestic and wild ruminants.
Silvia Turco, Simone Russo, Daniele Pietrucci, Anita Filippi, Marco Milanesi, Camilla Luzzago, Chiara Garbarino, Giorgia Palladini, Giovanni Chillemi, Giovanni Chillemi, Matteo Ricchi   +10 more
doaj   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, Volume 599, Issue 9, Page 1203-1221, May 2025.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Immunoreactivity of the Mycobacterium avium subsp. paratuberculosis 19-kDa lipoprotein

BMC Microbiology, 2005
Background The Mycobacterium tuberculosis 19-kDa lipoprotein has been reported to stimulate both T and B cell responses as well as induce a number of Th1 cytokines. In order to evaluate the Mycobacterium avium subsp. paratuberculosis (M.
Stabel Judith R, Huntley Jason FJ, Bannantine John P   +2 more
doaj   +1 more source

Mycobacterium avium Subspecies paratuberculosis Recombinant Proteins Modulate Antimycobacterial Functions of Bovine Macrophages. [PDF]

PLoS ONE, 2015
It has been shown that Mycobacterium avium subspecies paratuberculosis (M. paratuberculosis) activates the Mitogen Activated Protein Kinase (MAPK) p38 pathway, yet it is unclear which components of M.
John P Bannantine, Judith R Stabel, Elizabeth Laws, Maria Clara D Cardieri, Cleverson D Souza   +4 more
doaj   +1 more source

Assessment of Healthcare Professionals' Knowledge Regarding Nontuberculosis Mycobacterial Infections at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2024: A Cross‐Sectional Study

Journal of Clinical Laboratory Analysis, Volume 39, Issue 10, May 2025.
A comprehensive and schematic illustration of the study's methods and materials. ABSTRACT Background Nontuberculosis mycobacteria (NTM) are environmental pathogens that can cause pulmonary infections, especially among the immunocompromised population. There is limited research on healthcare professionals' knowledge of NTM infections in Ethiopia.
Teklehaimanot Kiros, Mulat Erkihun, Bekele Sharew, Andargachew Almaw, Ayenew Assefa, Tegenaw Tiruneh, Birhanu Getie, Yenealem Solomon, Shewaneh Damtie   +8 more
wiley   +1 more source