Results 51 to 60 of about 7,531 (254)

Transposon Mutagenesis in Mycobacterium avium Subspecies Paratuberculosis

, 2019
While transposon mutagenesis has been developed for Mycobacterium avium subspecies paratuberculosis (Map), relatively few laboratories have adopted this important genetic tool to examine gene function and essentiality. Here we describe the construction of a Map transposon library using the Himar1 mariner transposon, but concepts can also be applied to ...
Bannantine, John P., Zinniel, Denise K., Barletta, Raul G.   +2 more
openaire   +3 more sources

Genomic and transcriptomic studies in Mycobacterium avium subspecies paratuberculosis

Veterinary Immunology and Immunopathology, 2010
Microarray technology is an important tool in functional genomic research. It has enabled a deeper analysis of genomic diversity among bacteria belonging to the Mycobacterium avium complex (MAC). In addition, the expression of thousands of genes can be studied simultaneously in a single experiment.
Bannantine, J. P., Talaat, Adel M.
openaire   +3 more sources

A Major Cell Wall Lipopeptide of Mycobacterium avium subspecies paratuberculosis [PDF]

Journal of Biological Chemistry, 2006
Mycobacterium avium subspecies paratuberculosis (MAP), the causative agent of Johne disease in cattle and other ruminants, is proposed to be at least one of the causes of Crohn disease in humans. MAP and Mycobacterium avium subspecies avium, a closely related opportunistic environmental bacterium, share 95% of their genes and exhibit homologies of more
Torsten M, Eckstein, Sukantha, Chandrasekaran, Sebabrata, Mahapatra, Michael R, McNeil, Delphi, Chatterjee, Christopher D, Rithner, Philip W, Ryan, John T, Belisle, Julia M, Inamine   +8 more
openaire   +2 more sources

Molecular and Serological Footprints of Mycobacterium avium Subspecies Infections in Zoo Animals

Veterinary Sciences, 2020
Background: Mycobacteria of the Mycobacterium avium complex (MAC) pose a significant risk to zoological collections. Mycobacterium avium subspecies paratuberculosis (MAP) is a member of MAC and the causative agent of Johne’s disease. Despite many reports
Marco Roller, Sören Hansen, Susanne Böhlken-Fascher, Tobias Knauf-Witzens, Claus-Peter Czerny, Ralph Goethe, Ahmed Abd El Wahed   +6 more
doaj   +1 more source

Limitations of variable number of tandem repeat typing identified through whole genome sequencing of Mycobacterium avium subsp. paratuberculosis on a national and herd level [PDF]

, 2015
Background: Mycobacterium avium subsp. paratuberculosis (MAP), the causative bacterium of Johne’s disease in dairy cattle, is widespread in the Canadian dairy industry and has significant economic and animal welfare implications. An understanding of the
Ahlstrom, Christina, Barkema, Herman W., Biek, Roman, De Buck, Jeroen, Fecteau, Gilles, Haupstein, Deb, Kao, Rowland, Keefe, Greg P., Kelton, David F., Labrecque, Olivia, McKenna, Shawn L. B., Stevenson, Karen, Trewby, Hannah, Zadoks, Ruth N.   +13 more
core   +1 more source

Bovine Immunity and Vitamin D₃: An Emerging Association in Johne’s Disease

Microorganisms, 2022
Mycobacterium avium subspecies paratuberculosis (MAP) is an environmentally hardy pathogen of ruminants that plagues the dairy industry. Hallmark clinical symptoms include granulomatous enteritis, watery diarrhea, and significant loss of body condition ...
Taylor L. T. Wherry, Judith R. Stabel
doaj   +1 more source

Presence of Mycobacterium avium Subspecies paratuberculosis Monitored Over Varying Temporal and Spatial Scales in River Catchments:Persistent Routes for Human Exposure [PDF]

, 2019
Mycobacterium avium subspecies paratuberculosis (Map) was monitored by quantitative PCR over a range of temporal and spatial scales in the River Tywi catchment.
Bo, Bull, Caldow, Kuenstner, Mardia, McCullagh, Naser, Niegowska, Over, Poupart, Rhodes, Sorensen, Thorel, Wolf   +13 more
core   +6 more sources

The Broad Street pump revisited: dairy farms and an ongoing outbreak of inflammatory bowel disease in Forest, Virginia

Gut Pathogens, 2011
We report an ongoing outbreak of ulcerative colitis and Crohn's disease in Forest, Virginia involving 15 unrelated children and teenagers who resided in close proximity to dairy farms.
Pierce Ellen S, Borowitz Stephen M, Naser Saleh A   +2 more
doaj   +1 more source

The Mycobacterium avium Subspecies Paratuberculosis Dilemma

Biology and Medicine, 2015
The purpose of this paper is to present and update the longitudinal perspective of the Mycobacterium avium subspecies paratuberculosis dilemma as initially stated in Infectious Diseases Incorporated’s 2012 White Paper. In both wild and domestic herbivores, Mycobacterium avium subspecies paratuberculosis (MAP) produces chronic granulomatous enteritis ...
openaire   +1 more source

Enzyme-linked immunospot: an alternative method for the detection of interferon gamma in Johne's disease [PDF]

, 2009
. To date, the sensitivity of the interferon gamma (IFN-c) enzyme-linked immunosorbent assay (ELISA) to detect Johne’s disease (JD) has been poor, especially in the early stages of disease.
Begg, Douglas J., Bosward, Katrina, de Silva, Kumudika, Di Fiore, Lyrissa, Jungersen, Gregers, Taylor, Deborah, Whittington, Richard J.   +6 more
core   +2 more sources