Results 51 to 60 of about 12,706 (239)

Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

Vaccines, 2021
Heterologous prime-boost strategies are known to substantially increase immune responses in viral vectored vaccines. Here we report on safety and immunogenicity of the poxvirus Modified Vaccinia Ankara (MVA) vectored vaccine expressing four Mycobacterium
Pedro M. Folegatti, Amy Flaxman, Daniel Jenkin, Rebecca Makinson, Lucy Kingham-Page, Duncan Bellamy, Fernando Ramos Lopez, Jonathan Sheridan, Ian Poulton, Jeremy Aboagye, Nguyen Tran, Celia Mitton, Rachel Roberts, Alison M. Lawrie, Adrian V. S. Hill, Katie J. Ewer, Sarah Gilbert   +16 more
doaj   +1 more source

Genomic homogeneity between Mycobacterium avium subsp. avium and Mycobacterium avium subsp. paratuberculosis belies their divergent growth rates

BMC Microbiology, 2003
Background Mycobacterium avium subspecies avium (M. avium) is frequently encountered in the environment, but also causes infections in animals and immunocompromised patients.
Li Ling-Ling, Zhang Qing, Bannantine John P, Kapur Vivek   +3 more
doaj   +1 more source

Genetic Diversity Among Mycobacterium avium Subspecies Revealed by Analysis of Complete Genome Sequences

Frontiers in Microbiology, 2020
Mycobacterium avium comprises four subspecies that contain both human and veterinary pathogens. At the inception of this study, twenty-eight M. avium genomes had been annotated as RefSeq genomes, facilitating direct comparisons.
John P. Bannantine, Cyril Conde, Darrell O. Bayles, Maxime Branger, Franck Biet   +4 more
doaj   +1 more source

Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains [PDF]

, 2013
BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks
Bull, TJ, Greene, M, Linedale, R, McKendrick, IJ, Sales, J, Schock, A, Sharp, JM, Stevenson, K   +7 more
core   +1 more source

A novel multi-antigen virally vectored vaccine against Mycobacterium avium subspecies paratuberculosis.

PLoS ONE, 2007
BackgroundMycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including primates. Humans are exposed through milk and from sources of environmental contamination.
Tim J Bull, Sarah C Gilbert, Saranya Sridhar, Richard Linedale, Nicola Dierkes, Karim Sidi-Boumedine, John Hermon-Taylor   +6 more
doaj   +1 more source

Novel single nucleotide polymorphism-based assay for genotyping Mycobacterium avium subsp. paratuberculosis [PDF]

, 2016
Typing of Mycobacterium avium subspecies paratuberculosis strains presents a challenge, since they are genetically monomorphic and traditional molecular techniques have limited discriminatory power.
Bryant, Josephine, Goldstone, Robert J., Inácio, João, Leão, Célia, McLuckie, Joyce, Smith, David G.E., Stevenson, Karen   +6 more
core   +2 more sources

Estimating the sensitivity and specificity of serum ELISA and pooled and individual fecal PCR for detecting Mycobacterium avium subspecies paratuberculosis in Canadian cow-calf herds using Bayesian latent class models

Frontiers in Veterinary Science, 2022
While Johne's disease (JD) is less common in beef than in dairy herds, consolidation is increasing transmission risk. Estimates of Mycobacterium avium spp.
Paisley A. Johnson, Lianne McLeod, J. Campbell, M. Rousseau, K. Larson, C. Waldner   +5 more
semanticscholar   +1 more source

Research on Mycobacterium avium during the period 1995 to 2009

Veterinární Medicína, 2010
Papers on Mycobacterium avium, published between 1995 and 2009 that are indexed in the databases Web of Science® (Thomson Reuters) and PubMed (U.S.
M. Kaevska, K. Hruska
doaj   +1 more source

A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. [PDF]

, 2009
BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes.
Bull, TJ, Hermon-Taylor, J, Hinds, J, Linedale, R   +3 more
core   +3 more sources

Functional Variants Surrounding Endothelin 2 Are Associated With Mycobacterium avium Subspecies paratuberculosis Infection

Frontiers in Veterinary Science, 2021
Bovine paratuberculosis, caused by Mycobacterium avium subspecies paratuberculosis (MAP), continues to impact the dairy industry through increased morbidity, mortality, and lost production.
J. Kiser, Zeping Wang, R. Zanella, E. Scraggs, M. Neupane, B. Cantrell, C. V. Van Tassell, S. White, Jeremy F. Taylor, H. Neibergs   +9 more
semanticscholar   +1 more source