Results 91 to 100 of about 2,553 (217)

Persistence of legionella in routinely disinfected heater-cooler units and heater units assessed by propidium monoazide QPCR [PDF]

, 2020
Background: Evidence to date indicates that heater–cooler units (HCUs) and heater units (HUs) can generate potentially infectious aerosols containing a range of opportunistic pathogens such as Mycobacterium chimaera, other non-tuberculous ...
Ditommaso, S., Garlasco, J., Giacomuzzi, M., Memoli, G., Zotti, C. M.   +4 more
core   +1 more source

Improving diagnostic approaches in extensively and multidrug resistant tuberculosis: new diagnostic tools and repurposing drugs against X/MDRTB [PDF]

, 2022
Tuberculosis remains a major killer worldwide. Accurate, fast, and accessible diagnostics for both the disease and drug resistance remain challenges for tuberculosis (TB) control.
Gonzalo, Ximena
core   +1 more source

Small Molecule‐Based Conditional Gene Regulation: Advances and Applications

Chemistry–Methods, Volume 6, Issue 4, April 2026.
The precise, temporal, and reversible control of gene expression using small molecule ligands is crucial for understanding complex cellular functions and is rapidly advancing the field of synthetic biology. Small molecule‐mediated conditional gene regulation has widespread applications, including bio‐manufacturing, cellular reprogramming, gene therapy,
Mohd Afaque Ansari, Riddhima Sharma, Priyanka Swami, Ambadas B. Rode   +3 more
wiley   +1 more source

Characterization of a novel variant of Mycobacterium chimaera

Journal of Medical Microbiology, 2012
In this study, nonchromogenic mycobacteria were isolated from pulmonary samples of three patients in the Netherlands. All isolates had identical, unique 16S rRNA gene and 16S-23S ITS sequences, which were closely related to those of Mycobacterium chimaera and Mycobacterium marseillense.
van Ingen, J., Hoefsloot, W., Hoefsloot, W., Buijtels, P.C., Tortoli, E., Supply, P., Dekhuijzen, P.N.R., Boeree, M.J., van Soolingen, D.   +8 more
openaire   +5 more sources

Tn‐seq of Thermus thermophilus Genome Reveals Unexpected Tolerance to Insertions in Bacterial Common Essential Genes

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Tn‐seq analysis of Thermus thermophilus genome reveals insertions in almost all genes, this is, there is no clear discrimination of essential genes. A similar result has not been reported in other Tn‐seq analysis of bacterial genomes so far. The polyploidy of the Thermus genome could explain the apparent non‐essentiality of key genes.
Cristina L. Gómez‐Campo, Marc Gost, Bruna Fernanda Silva de Sousa, Laura Álvarez, José Berenguer, Modesto Redrejo‐Rodríguez, Mario Mencía   +6 more
wiley   +1 more source

Insidious risk of severe mycobacterium chimaera infection in cardiac surgery patients [PDF]

, 2016
Background. An urgent UK investigation was launched to assess risk of invasive Mycobacterium chimaera infection in cardiothoracic surgery and a possible association with cardiopulmonary bypass heater-cooler units following alerts in Switzerland and The ...
Ahmed, Nada, Bennett, Allan, Bhatt, Sonia, Brown, Tim, Carrion Martin, Antonio Isidro, Chand, Meera, Charlett, André, Collins, Samuel, Collyns, Tim, Crook, Derrick, Davies, Eleri, Del Ojo Elias, Carlos, Doherty, Lorraine, Dolan, Gayle, Hedge, Jessica, Hoffman, Peter, Kendall, Simon, Kirwan, Peter, Klein, Andrew A., Kranzer, Katharina, Lalor, Maeve K., Lamagni, Theresa, Mason, Brendan, McMenamin, Jim, Moore, Ginny, Newsholme, William, Parks, Simon, Pearce, David, Peto, Tim E.A., Phin, Nick, Robins, Stephen, Russell, Katherine, Schelenz, Silke, Skingsley, Andrew, Smith, E. Grace, Smith-Palmer, Alison, Thomas, Stephanie, Veal, Philip, Walker, James, Yeap, Alicia, Zambon, Maria   +40 more
core   +1 more source

Soil and Genotype Shape the Sugarcane Phytobiome for Enhanced Environmental Adaptation

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Soil type and sugarcane genotype, differing in their adaptability to low‐fertility soils, interact to shape microbial recruitment and host transcriptional responses. In sandy soils, the better‐adapted genotype IACSP‐5503 recruits more plant growth‐promoting bacteria and activates growth‐related genes, while in clayey soils the less‐adapted IACSP‐6007 ...
J. D. Ferreti, B. Ribeiro, J. de A. Bonetti, L. E. A. Camargo, S. Creste, E. E. Kuramae, C. B. Monteiro‐Vitorello   +6 more
wiley   +1 more source

Rapid detection of invasive Mycobacterium chimaera disease via a novel plasma-based next-generation sequencing test

BMC Infectious Diseases, 2019
Background There is an ongoing outbreak of Mycobacterium chimaera infections among patients exposed to contaminated heater-cooler devices used during cardiac surgery. Recognition of M.
Jim Nomura, Gunter Rieg, Gary Bluestone, Townson Tsai, Andrew Lai, Dawn Terashita, Sivan Bercovici, David K. Hong, Brian P. Lee   +8 more
doaj   +1 more source

Mycobacterium chimaera – a new threat for cardiac surgical patients?

Polish Journal of Cardio-Thoracic Surgery, 2017
An outbreak of invasive Mycobacterium chimaera infections associated with "heater-cooler" devices in patients treated with cardiac surgery has been described worldwide. The authors summarize the current state of knowledge regarding the epidemiology, diagnostics, treatment, and prevention of Mycobacterium chimaera infections in patients after ...
Jaworski, Radosław, Naumiuk, Łukasz, Paczkowski, Konrad, Formella, Danuta, Pek, Renata, Zieliński, Jacek, Haponiuk, Ireneusz   +6 more
openaire   +2 more sources

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, Volume 4, Issue 2, March 2026.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source