Results 81 to 90 of about 187,712 (288)
Oral treatment with HSP65‐producing Lactococcus lactis after Leishmania braziliensis infection modulates inflammation by promoting lesion resolution through increased IL‐10 production and expansion of regulatory T cells. These findings highlight the potential of oral tolerance induction as a promising therapeutic strategy for chronic inflammatory ...
Camila Mattos Andrade +11 more
wiley +1 more source
Schistosoma haematobium infection and Buruli ulcer [PDF]
No abstract ...
Aguiar, Julia +7 more
core +3 more sources
Importance of the immune response to Mycobacterium leprae in the skin
The causative agent of leprosy is Mycobacterium leprae (M. leprae), which establishes infectious lesions in the skin. Leprosy is classified based on the clinical manifestation, the host’s immune response and skin symptoms. M.
Song-Hyo Jin, K. Ahn, S. An
semanticscholar +1 more source
A Mycobacterium leprae VNTR database [PDF]
A great deal of the last quarter of a century’s astonishing progress in understanding and treating human disease is attributable to the existence of public databases where information about DNA sequences, protein sequences, protein structures, human variation, etc. is stored and is freely available to all interested investigators.
openaire +2 more sources
From leprosy to ground zero: Imagining futures in a world of elimination
Abstract Achieving a target of zero—zero disease, zero disability, and zero discrimination—has become the dominant focus of campaigns to control or eliminate diseases, from HIV/AIDS to malaria to leprosy. Given the historical failure of most eradication programs over the last century, such teleological imaginings of disease‐free futures might seem ...
James Staples
wiley +1 more source
Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017
Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to ...
Qingtian Guan +4 more
doaj +1 more source
Leprosy is a human infectious disease caused by Mycobacterium leprae. A strong host genetic contribution to leprosy susceptibility is well established. However, the modulation of the transcriptional response to infection and the mechanism(s) of disease ...
J. Manry +9 more
semanticscholar +1 more source
Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso +5 more
wiley +1 more source
Length, Protein-Protein Interactions, and Complexity
The evolutionary reason for the increase in gene length from archaea to prokaryotes to eukaryotes observed in large scale genome sequencing efforts has been unclear.
Albert +27 more
core +1 more source
Neopterin is a sensitive and specific biomarker of intracellular pathogen infection and chronic inflammation, and affected by environmental, life‐history, and sex‐contextual factors. This review offers best‐practice guidelines and practical advice on sample collection, storage, and analysis in primates when used for ecoimmunological conservation and ...
Verena Behringer, Caroline Deimel
wiley +1 more source

