Widespread Skin Lesions in an Italian Man
JEADV Clinical Practice, Volume 5, Issue 1, Page 333-336, March 2026.
Rebecca Donadoni +7 more
wiley +1 more source
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
Drug Development Research, Volume 86, Issue 8, December 2025.ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source
Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery
Emerging Microbes and Infections, 2019 Of the more than 190 distinct species of Mycobacterium genus, many are economically and clinically important pathogens of humans or animals. Among those mycobacteria that infect humans, three species namely Mycobacterium tuberculosis (causative agent of ...
Vaishali P. Waman +7 more
doaj +1 more source
Two pathogens, one disease: Rethinking leprosy diversification through ancient and modern genomes
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Maria Lopopolo +2 more
wiley +1 more source
Exploring prospects of novel drugs for tuberculosis [PDF]
, 2012 Tuberculosis remains a disease with an enormous impact on public health worldwide. With the continuously increasing epidemic of drug-resistant tuberculosis, new drugs are desperately needed. However, even for the treatment of drug-sensitive tuberculosis,
Grobusch, M. P. +5 more
core +1 more source
Recent advances in nontuberculous mycobacterial lung infections [version 1; peer review: 2 approved]
F1000Research, 2019 Nontuberculous mycobacteria (NTM) are members of the Mycobacterium genus other than Mycobacterium tuberculosis complex and Mycobacterium leprae. NTM are widely distributed in the environment and are increasingly recognized as causes of chronic lung ...
David Horne, Shawn Skerrett
doaj +1 more source
Identification of T cell stimulatory epitopes from the 18 kDa protein of Mycobacterium leprae [PDF]
, 2017 We have used different mouse strains to examine in vivo and in vitro responses to the 18 kDa protein of Mycobacterium leprae, which appears to be strongly immunogenic in both mice and humans.
Bäckström, B. Thomas +4 more
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Intracellular
mBio, 2019 New approaches are needed to control leprosy, but understanding of the biology of the causative agent Mycobacterium leprae remains rudimentary, principally because the pathogen cannot be grown in axenic culture.
Khushboo Borah +7 more
doaj +1 more source
Leprosy in Nonimmigrant Canadian Man without Travel outside North America, 2014
Emerging Infectious Diseases, 2018 In Canada, Hansen disease (leprosy) is rare and not considered in diagnoses for nonimmigrant patients. We report Mycobacterium leprae infection in a Canadian man whose sole travel was to Florida, USA. The M.
Paul E. Bonnar +5 more
doaj +1 more source
The interplay of DNA and lipid biomarkers in the detection of tuberculosis and leprosy in mummies and other skeletal remains [PDF]
, 2011 The detection of ancient DNA and lipid biomarkers has become established for the detection of tuberculosis and leprosy in archaeological material, including mummies.
Besra, GS +4 more
core