Results 81 to 90 of about 174,365 (247)
The FEBS Journal, Volume 292, Issue 19, Page 5234-5243, October 2025.The adenylyl cyclase (AC) Rv1625c from M. tuberculosis is a monomeric progenitor of the nine pseudoheterodimeric mammalian AC isoforms. The hexahelical membrane anchor of Rv1625c serves as an inhibitory receptor for fatty acids, particularly oleic acid. One ligand binds into each monomer of the active Rv1625c dimer.
Anita Charlotte Friderun Schultz +3 more
wiley +1 more source
PLoS Neglected Tropical Diseases, 2016 Background The persistence of Mycobacterium leprae (M. leprae) infection is largely dependent on the types of host immune responses being induced. Macrophage, a crucial modulator of innate and adaptive immune responses, could be directly infected by M ...
De-gang Yang +9 more
semanticscholar +1 more source
Tropical Medicine &International Health, Volume 30, Issue 10, Page 1115-1123, October 2025.ABSTRACT Leprosy presents a broad clinical spectrum influenced by the host's immune response, and co‐infections may further modulate disease progression. This study evaluated clinically diagnosed leprosy patients (n = 251) from Sergipe and Minas Gerais, Brazil, along with healthy controls (n = 43), soil‐transmitted helminths‐positive controls (n = 15),
Ana Laura Grossi de Oliveira +9 more
wiley +1 more source
Recent advances in nontuberculous mycobacterial lung infections [version 1; peer review: 2 approved]
F1000Research, 2019 Nontuberculous mycobacteria (NTM) are members of the Mycobacterium genus other than Mycobacterium tuberculosis complex and Mycobacterium leprae. NTM are widely distributed in the environment and are increasingly recognized as causes of chronic lung ...
David Horne, Shawn Skerrett
doaj +1 more source
Mycobacterium leprae alters classical activation of human monocytes in vitro
Journal of Inflammation, 2016 BackgroundMacrophages play a central role in the pathogenesis of leprosy, caused by Mycobacterium leprae. The polarized clinical presentations in leprosy are associated with differential immune activation.
D. Fallows +3 more
semanticscholar +1 more source
Leprosy in Nonimmigrant Canadian Man without Travel outside North America, 2014
Emerging Infectious Diseases, 2018 In Canada, Hansen disease (leprosy) is rare and not considered in diagnoses for nonimmigrant patients. We report Mycobacterium leprae infection in a Canadian man whose sole travel was to Florida, USA. The M.
Paul E. Bonnar +5 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2016 Toll-like receptor (TLR)-1 and TLR2 have been shown to be receptors for Mycobacterium leprae (M. leprae), yet it is unclear whether M. leprae can signal through alternative TLRs.
A. Polycarpou +6 more
semanticscholar +1 more source
Presence of viable Mycobacterium leprae in environmental specimens around houses of leprosy patients
Indian Journal of Medical Microbiology, 2016 Purpose: Leprosy is a chronic systemic infectious disease caused by Mycobacterium leprae, one of the first organisms to be established as the cause for disease in humans.
R. Turankar +5 more
semanticscholar +1 more source
PLoS ONE, 2016 Leprosy is a chronic dermato-neurological disease caused by infection with Mycobacterium leprae. In 2013 almost 200,000 new cases of leprosy were detected around the world.
A. S. Neumann +13 more
semanticscholar +1 more source
A rare case of lepromatous leprosy in Germany
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 11, Page 1454-1456, November 2025.
Roman Saternus +8 more
wiley +1 more source