Results 61 to 70 of about 26,862 (225)

Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

open access: yesEmerging Infectious Diseases, 2020
Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to ...
Qingtian Guan   +4 more
doaj   +1 more source

A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies

open access: yesAnalysis &Sensing, Volume 6, Issue 2, March 2026.
An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro   +7 more
wiley   +1 more source

De Novo Histoid Leprosy Mimicking Xanthoma Disseminatum in a Malawian Male

open access: yesProceedings
Background: Leprosy is a chronic infection caused by Mycobacterium leprae and Mycobacterium lepromatosis with protean mucocutaneous manifestations [...]
Agnes Ramadimetja Sema-Ramashala   +1 more
doaj   +1 more source

Modulation of the Response to Mycobacterium leprae and Pathogenesis of Leprosy

open access: yesFrontiers in Microbiology, 2022
The initial infection by the obligate intracellular bacillus Mycobacterium leprae evolves to leprosy in a small subset of the infected individuals. Transmission is believed to occur mainly by exposure to bacilli present in aerosols expelled by infected ...
Natasha Cabral   +9 more
doaj   +1 more source

Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D. [PDF]

open access: yes, 2014
Acne vulgaris is the most common skin disorder affecting millions of people worldwide and inflammation resulting from the immune response targeting Propionibacterium acnes has a significant role in its pathogenesis.
Agak, George W   +8 more
core  

In vitro activity of bedaquiline against rapidly growing nontuberculous mycobacteria [PDF]

open access: yes, 2017
Bedaquiline (BDQ) has been proven to be effective in the treatment of multidrug-resistant tuberculosis. We hypothesized that BDQ could be a potential agent to treat nontuberculous mycobacterial (NTM) infection. The objective of this study was to evaluate
Aguilar-Ayala, Diana   +7 more
core   +2 more sources

Development and validation of a multiplex real-time qPCR assay using GMP-grade reagents for leprosy diagnosis.

open access: yesPLoS Neglected Tropical Diseases, 2022
Leprosy is a chronic dermato-neurological disease caused by Mycobacterium leprae, an obligate intracellular bacterium. Timely detection is a challenge in leprosy diagnosis, relying on clinical examination and trained health professionals.
Fernanda Saloum de Neves Manta   +13 more
doaj   +1 more source

Severe and disseminated atypical mycobacteriosis of the skin under immunosuppression

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Veronika Zenderowski   +6 more
wiley   +1 more source

Type 2 Lepra Reaction Following Antituberculosis Treatment Initiation in an Elderly Male With Coexisting Hansen's Disease: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 3, March 2026.
We report a case of a man developing erythema nodosum leprosum after initiating treatment for drug‐susceptible pulmonary tuberculosis. This highlights the importance of recognising concomitant leprosy in patients with tuberculosis since these mycobacterial infections require different long‐term multidrug regimens.
Cary Amiel G. Villanueva   +3 more
wiley   +1 more source

Skeletal Evidence for Leprosy in India by the Second Millenium B.C. [PDF]

open access: yes, 2009
Leprosy is a chronic infectious disease caused by _Mycobacterium leprae_ that affects almost 500,000 people worldwide^1^. The timing of first infection, geographic origin, and pattern of transmission of the disease are unknown^1-3^.
Gwendolyn Robbins   +6 more
core   +1 more source

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