Results 1 to 10 of about 10,973 (118)

Levamisole as a Strategy Against Bacteria from Canine Otitis Externa: An In Vitro Evaluation [PDF]

Veterinary Sciences
Canine otitis externa is a prevalent condition, and inadequate treatment may favor the emergence of multidrug-resistant microorganisms. Drug repurposing provides an alternative approach for the management of this disease.
Rodrigo F. M. Guedes, Ana C. C. F. Soares, Francisco I. F. Gomes, Alyne S. Freitas, Vinicius C. Pereira, Rossana A. Cordeiro, Marcos F. G. Rocha, José J. C. Sidrim, Giovanna R. Barbosa, Glaucia M. M. Guedes, Debora S. C. M. Castelo-Branco   +10 more
doaj   +2 more sources

Research on the Removal of Levamisole Residues in Bovine, Ovine, Caprine, Porcine and Poultry Tissues

Separations, 2022
In this paper, we set the waiting time for the elimination of levamisole residues at a safe level from tissues (muscles and organs) from animals treated with levamisole 10%—oral solution.
Viviana Carmen Ciucă, Carmen Otilia Rusănescu, Victor Viorel Safta   +2 more
doaj   +1 more source

Levamisole Modulation of Podocytes’ Actin Cytoskeleton in Nephrotic Syndrome

Biomedicines, 2023
Podocytes play a central role in glomerular diseases such as (idiopathic) nephrotic syndrome (iNS). Glucocorticoids are the gold standard therapy for iNS. Nevertheless, frequent relapses are common.
Susan T. Veissi, Tijmen van den Berge, Joanna A. E. van Wijk, Thea van der Velden, René Classens, Lynn Lunsonga, Rick Brockotter, Charlotte Kaffa, Sander Bervoets, Bart Smeets, Lambertus P. W. J. van den Heuvel, Michiel F. Schreuder   +11 more
doaj   +1 more source

Time to remission in first episode of Idiopathic Nephrotic Syndrome in children with response to Levamisole in subsequent relapses

Indian Journal of Kidney Diseases, 2022
Background: Idiopathic nephrotic syndrome (NS) is the most common cause for NS in children. While it responds to steroids in most instances, relapses are also common.
Pankaj Deshpande
doaj   +1 more source

Tribendimidine: mode of action and nAChR subtype selectivity in Ascaris and Oesophagostomum. [PDF]

PLoS Neglected Tropical Diseases, 2015
The cholinergic class of anthelmintic drugs is used for the control of parasitic nematodes. One of this class of drugs, tribendimidine (a symmetrical diamidine derivative, of amidantel), was developed in China for use in humans in the mid-1980s. It has a
Alan P Robertson, Sreekanth Puttachary, Samuel K Buxton, Richard J Martin   +3 more
doaj   +1 more source

Multifocal leukoencephalopathy associated with intensive use of cocaine and the adulterant levamisole in a 29-year old patient

Neurological Research and Practice, 2022
Levamisole is a common adulterant of cocaine and has been associated with reversible leukoencephalopathy in cocaine users. We report a case of two episodes with severe neurological symptoms and multifocal white matter lesions with brainstem and ...
Nadine Tollens, Philip Post, Michael Martins Dos Santos, Pascal Niggemann, Melanie Warken, Joachim Wolf   +5 more
doaj   +1 more source

Rare presentation of levamisole-induced leukoencephalopathy in a pediatric patient: seizure

The Turkish Journal of Pediatrics, 2021
Background. Levamisole is an imidazole derivative used in the treatment of various cancers, dermatological diseases, and parasitosis. Illegal use of levamisole by mixing it with cocaine in order to increase the psychotropic effects has also ...
Cem Paketçi, Derya Okur, Semra Hız, Uluç Yiş   +3 more
doaj   +1 more source

Studies on 3H-levamisole binding to murine splenic lymphocytes, normal, malignant human lymphocytes and fate of levamisole in cell culture

Biomedical and Biotechnology Research Journal, 2018
Background: Levamisole at high concentrations has been shown to have anticancer and immunosuppressive actions. Methods: In the present study, fate of levamisole in cell culture and 3 H-levamisole binding to murine splenic lymphocytes, normal and ...
B Nageshwari, Ramchander Merugu
doaj   +1 more source

Levamisole-Induced immune phenomenon and its various clinical manifestations in children: Two case reports along with review of literature

Indian Journal of Rheumatology, 2021
In literature, levamisole-induced immune manifestations were described mostly in association with its use in treatment of rheumatoid arthritis, malignancies, and recently, in relation to the use of illicit cocaine contaminated with levamisole among ...
Anu Punnen Kocheril, T Sathish Kumar, Dharshini Sathishkumar   +2 more
doaj   +1 more source

Treatment effectiveness of levamisole plus prednisolone on oral lichen planus patients with emphasis on levamisole-induced agranulocytosis or pancytopenia

Journal of the Formosan Medical Association, 2019
Background/Purpose: Physicians' and dentists' knowledge of levamisole-induced agranulocytosis or pancytopenia remains incomplete. This study aimed to evaluate the treatment effectiveness of levamisole plus prednisolone on oral lichen planus (OLP ...
Shin-Yu Lu, Tzu-Fan Chang, Chih-Jen Lin
doaj   +1 more source