Results 51 to 60 of about 11,881 (182)

Demyelinating Leprosy Neuropathy: An Unusual and Misleading Electrophysiological Pattern

Muscle &Nerve, Volume 73, Issue 5, Page 898-905, May 2026.
ABSTRACT Introduction/Aims Peripheral neuropathy, especially mononeuropathy multiplex, is a frequent manifestation of leprosy. Electrodiagnostic studies (EDX) usually show predominant axonal involvement. In this study, we report patients with prominent demyelinating abnormalities consistent with the diagnosis of chronic inflammatory demyelinating ...
Cendrine Foucard, Marie Jachiet, Karine Viala, Thierry Maisonobe, Guillaume Fargeot   +4 more
wiley   +1 more source

M. leprae inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression

BMC Microbiology, 2006
Background Virulent Mycobacterium leprae interfere with host defense mechanisms such as cytokine activation and apoptosis. The mitochondrial pathway of apoptosis is regulated by the Bcl-2 family of proteins.
Tayyebi Ali, Ashraf Mussarat, Hasan Zahra, Hussain Rabia   +3 more
doaj   +1 more source

A Quantitative Approach to Record Skeletal Manifestations of Leprosy and Its Application to St Mary Magdalen Leprosarium, Winchester

International Journal of Osteoarchaeology, Volume 36, Issue 3, Page 526-536, May/June 2026.
ABSTRACT This paper presents and tests a new method for publishing and diagnosing leprosy‐related skeletal lesions while making available the leprosy‐related demographic data and pathology for St Mary Magdalen, Winchester (MMW). This method can facilitate interstudy comparisons of leprosy prevalence and severity by improving data comparability.
A. A. Blom, H. Dawson‐Hobbis, S. Gross, K. White‐Iribhogbe, V. J. Schuenemann, S. A. Inskip   +5 more
wiley   +1 more source

Understanding the Distribution of Muscidae Flies and Their Role as Vectors of Bacterial Pathogens in South Africa: A Review Using BOLD Barcoding Data

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
ABSTRACT The role of Muscidae flies as vectors of bacterial pathogens with veterinary and public health significance necessitates accurate species identification and distribution mapping. This review analysed records from the Barcode of Life Data Systems (BOLD) and the South African National Biodiversity Institute (SANBI) national Diptera checklist ...
Veronica Phetla, Monica Mwale, Oriel Thekisoe, Maropeng Charles Monyama   +3 more
wiley   +1 more source

The role of red squirrels in leprosy dynamics in the United Kingdom: a critical review

One Health
In the United Kingdom, the declining population of the red squirrel, the acknowledged historical reservoir for zoonotic Mycobacterium leprae leprosy, is thought to have been behind the decline in leprosy.
S. Souguel, T. Oueslati, G. Grine, M. Drancourt   +3 more
doaj   +1 more source

Acidic pH Restricts Non‐Tuberculous Mycobacteria Replication

Molecular Microbiology, Volume 125, Issue 5, Page 375-388, May 2026.
Different nontuberculous mycobacteria (NTM) species display unique replication profiles in acidic pH in vitro which correlates to their replication within human macrophages. Inhibition of the acidic environments within the macrophage enhances bacterial viability emphasising the role of acidic pH during NTM infections.
Parise K. Lockwood, Luiz Pedro Sorio de Carvalho, Rachel P. J. Lai, Maximiliano G. Gutierrez   +3 more
wiley   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Perceptions of Hansen's Disease in Northeast Brazil: A Community‐Based Study Integrating Stigma, Empowerment, and Social Distance

Tropical Medicine &International Health, Volume 31, Issue 4, Page 465-480, April 2026.
ABSTRACT Perceptions of Hansen’s disease (HD) can influence the level of stigma, empowerment, and intention to distance oneself from those affected by the disease. Knowledge, attitudes, and beliefs shape these perceptions. This study aims to understand perceptions of HD regarding stigma and empowerment. Method: A cross‐sectional, mixed‐methods research
Jaqueline Caracas Barbosa, Aymée Medeiros da Rocha, Hellen Xavier Oliveira, Nágila Nathaly Lima Ferreira, Adriana da Silva dos Reis, Anderson Fuentes Ferreira, Wim H. van Brakel, Anna T. van ‘t Noordende, Duane Charles Hinders, José Alexandre Menezes da Silva, Carmem Emmanuely Leitão Araújo, Rômulo do Nascimento Rocha, Alberto Novaes Ramos Jr   +12 more
wiley   +1 more source

Ausgeprägte und disseminierte atypische Mykobakteriose der Haut unter Immunsuppression

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 6, Page 806-809, June 2026.
Veronika Zenderowski, Laura Schreieder, Mark Berneburg, Dennis Niebel, Sebastian Haferkamp, Sigrid Karrer, Konstantin Drexler   +6 more
wiley   +1 more source

A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies

Analysis &Sensing, Volume 6, Issue 2, March 2026.
An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro, Camila dos Anjos Proença, Ana Carolina da Rosa Nogarolli, Ana Fabiele Domakoski Trevisan, Thiago Neves Machado, João Carlos Degraf Muzzi, Larissa Magalhães Alvarenga, Juliana de Moura   +7 more
wiley   +1 more source