Results 31 to 40 of about 11,852 (180)

Mycobacterium leprae Infection in a Wild Nine-Banded Armadillo, Nuevo León, Mexico

Emerging Infectious Diseases, 2022
Nine-banded armadillos (Dasypus novemcinctus) are naturally infected with Mycobacterium leprae and are implicated in the zoonotic transmission of leprosy in the United States. In Mexico, the existence of such a reservoir remains to be characterized.
Lucio Vera-Cabrera, Cesar J. Ramos-Cavazos, Nathan A. Youssef, Camron M. Pearce, Carmen A. Molina-Torres, Ramiro Avalos-Ramirez, Sebastien Gagneux, Jorge Ocampo-Candiani, Mercedes Gonzalez-Juarrero, Jorge A. Mayorga-Rodriguez, Leonardo Mayorga-Garibaldi, John S. Spencer, Mary Jackson, Charlotte Avanzi   +13 more
doaj   +1 more source

Assessment of Antimicrobial Resistance in M. leprae Strains From Kiribati

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Kiribati has one of the highest rates of leprosy worldwide. A nationwide screening and chemoprophylaxis program for household leprosy contacts was introduced in 2018. In 2022, population‐wide screening and rifamycin‐based treatment or chemoprophylaxis for leprosy and tuberculosis was introduced as part of the PEARL and COMBINE ...
Patrick O. Campbell, Temea Bauro, Erei Rimon, Nabura Ioteba, Trevor Anderson, Arturo Cunanan, Taulanga Naniseni, Jacqui Gardner, Emma Trowbridge, Nicholas M. Douglas, Stephen T. Chambers   +10 more
wiley   +1 more source

Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe‐Host‐Interaction With the Most Complex Human Commensal, Demodex folliculorum

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller, S. Walch, S. Gschwendtner, A. Klingl, L. E. French, M. Flaig, B. M. Clanner‐Engelshofen   +6 more
wiley   +1 more source

Mycobacterium leprae [PDF]

, 2006
Although Mycobacterium leprae was one of the first bacterial pathogens of humans to be described (Hansen, 1874), progress on understanding the basic biology and pathogenicity of this organism has been greatly hampered by the inability to find a conventional laboratory medium or tissue culture system that can support its growth.
openaire   +2 more sources

Salivary anti-PGL-1 IgM may indicate active transmission of Mycobacterium leprae among young people under 16 years of age

Brazilian Journal of Infectious Diseases, 2017
Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection.
Alexandre Casimiro de Macedo, José Evandro Cunha, Jr., Juliana Navarro Ueda Yaochite, Clodis Maria Tavares, Aparecida Tiemi Nagao-Dias   +4 more
doaj   +1 more source

Peptidoglycan and Arabinogalactan of Mycobacterium Leprae [PDF]

Microbiology, 1987
The arabinogalactan and peptidoglycan of armadillo-grown Mycobacterium leprae were examined. Within the limits defined by the small amount of material available, the resemblance of these polymers to those of other mycobacteria was confirmed. The polymers were linked by a highly acid-labile bond and the arabinogalactan was itself acid-labile; free ...
P, Draper, O, Kandler, A, Darbre
openaire   +2 more sources

A case study of delayed-diagnosed leprosy: advancing diagnosis through MetaPath

International Journal of Infectious Diseases
Background: Leprosy, a chronic infectious disease caused by Mycobacterium leprae, can lead to sensory deficits, motor impairment, disability, and social stigma, imposing a dual physical and psychological burden on patients.
Yanhui Song, Xin Li, Cuili Li, Jing Xu, Feifei Liu, Zhiying Zhao, Xi Zhong   +6 more
doaj   +1 more source

Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae

Nature Communications, 2018
Leprosy is caused by the yet-uncultured pathogen Mycobacterium leprae. Here, Benjak et al. obtain M. leprae genome sequences from DNA extracted from patients' skin biopsies and, by analysing 154 genomes from 25 countries, provide insight into the ...
Andrej Benjak, Charlotte Avanzi, Pushpendra Singh, Chloé Loiseau, Selfu Girma, Philippe Busso, Amanda N. Brum Fontes, Yuji Miyamoto, Masako Namisato, Kidist Bobosha, Claudio G. Salgado, Moisés B. da Silva, Raquel C. Bouth, Marco A. C. Frade, Fred Bernardes Filho, Josafá G. Barreto, José A. C. Nery, Samira Bührer-Sékula, Andréanne Lupien, Abdul R. Al-Samie, Yasin Al-Qubati, Abdul S. Alkubati, Gisela Bretzel, Lucio Vera-Cabrera, Fatoumata Sakho, Christian R. Johnson, Mamoudou Kodio, Abdoulaye Fomba, Samba O. Sow, Moussa Gado, Ousmane Konaté, Mariane M. A. Stefani, Gerson O. Penna, Philip N. Suffys, Euzenir Nunes Sarno, Milton O. Moraes, Patricia S. Rosa, Ida M. F. Dias Baptista, John S. Spencer, Abraham Aseffa, Masanori Matsuoka, Masanori Kai, Stewart T. Cole   +42 more
doaj   +1 more source

Neurovascular–metabolic dysregulation, metabolic connectomics, and metabolic functional changes in Alzheimer's disease: A preclinical and clinical comparison

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract Historically, imaging diagnostics in Alzheimer's disease (AD) have focused primarily on amyloid and tau accumulation; however, recent work suggests that neurometabolic and vascular dysregulation (MVD) may precede protein deposition and persist throughout the disease spectrum, preclinically and clinically.
Juan Antonio K. Chong Chie, Scott A. Persohn, Olivia R. Simcox, Alyssa Collins, Paul Salama, Paul R. Territo, for the Alzheimer's Disease Neuroimaging Initiative and MODEL‐AD consortium   +6 more
wiley   +1 more source

“Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches—A Narrative Review”

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Reaction in leprosy is an immune‐mediated acute inflammatory episodes that occur in the natural course of Hansen's disease. Reaction can occur before, during, or after starting multidrug therapy and is a major cause of nerve damage, morbidity, and disability in affected individuals.
Bhaskar Gupta, Manesha Singh, Mohamad Goldust, Kinnor Das, Surajit Gorai, Prajwal Pudasaini, Seema Sitaula, Achyut Pokhrel, Esna Thapa, Sunil Jaiswal   +9 more
wiley   +1 more source