Results 11 to 20 of about 11,852 (180)

Sensitivity of Mycobacterium leprae to Telacebec [PDF]

open access: yesEmerging Infectious Diseases, 2022
The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis.
Ramanuj Lahiri   +3 more
doaj   +4 more sources

Lepra Bubalorum, a Potential Reservoir of Mycobacterium leprae [PDF]

open access: yesFrontiers in Microbiology, 2021
In 1926, a mycobacterial skin disease was observed in water buffaloes by researchers in Indonesia. The disease was designated as skin tuberculosis, though it was hypothesized that it might be a form of leprosy or a leprosy-like disease. In a follow-up study (Ph.D.
William R. Faber   +4 more
openaire   +5 more sources

Validation of qPCR Methods for the Detection of Mycobacterium in New World Animal Reservoirs. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
Zoonotic pathogens that cause leprosy (Mycobacterium leprae) and tuberculosis (Mycobacterium tuberculosis complex, MTBC) continue to impact modern human populations.
Genevieve Housman   +8 more
doaj   +1 more source

Métodos tintoriais utilizados na identificação do Mycobacterium leprae: revisão histológica Staining methods used in the identification of Mycobacterium leprae: historical review

open access: yesRevista de Saúde Pública, 1984
Foi feita revisão histórica sobre métodos tintoriais utilizados na identificação baciloscópica do Mycobacterium leprae. Ao lado da descrição de cada método, e suas variantes, é feita extensa revisão bibliográfica.A historical review of the staining ...
Luiz Fernando de Góes Siqueira   +2 more
doaj   +1 more source

Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Upon infection, Mycobacterium leprae, an obligate intracellular bacillus, induces accumulation of cholesterol-enriched lipid droplets (LDs) in Schwann cells (SCs). LDs are promptly recruited to M.
Thabatta L. S. A. Rosa   +17 more
doaj   +1 more source

Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos

open access: yesHansenologia Internationalis, 1983
Se estudió la inmunidad mediada por células (IMC) frente a derivados proteicos purificados de Mycobacterium leprae, Mycobacterium tuberculosis, Myco- bacterium avium y Mycobacterium marinum.
Enrique L. FLIESS   +2 more
doaj   +1 more source

Mycobacterium uberis Infection in the Subcutaneous Tissue of the Radius/Ulna Area of a Cow

open access: yesMicroorganisms, 2020
Mycobacterium uberis (M. uberis) is a recently described non-tuberculous mycobacterium phylogenetically close to Mycobacterium leprae (M. leprae) and Mycobacterium lepromatosis (M. lepromatosis).
Lorraine Michelet   +1 more
doaj   +1 more source

Intact Mycobacterium leprae Isolated from Placenta of a Pregnant Woman, China

open access: yesEmerging Infectious Diseases, 2019
Whether Mycobacterium leprae transmits from placenta to fetus remains unknown. We describe the case of a pregnant woman with untreated histoid leproma. Although her newborn was healthy, laboratory examination revealed intact M.
Zhiming Chen   +8 more
doaj   +1 more source

Clinical, histopathological, and molecular characterization of leprosy in an endemic area of the colombian caribbean

open access: yesInternational Journal of Mycobacteriology, 2021
Background: Mycobacterium leprae was considered the only causal agent of leprosy until Mycobacterium lepromatosis was identified' which it has been suggested has greater pathogenicity and is linked to diffuse lepromatous leprosy (DLL) and Lucio's ...
Maria Carolina Fragozo-Ramos   +4 more
doaj   +1 more source

Genetic diversity of Mycobacterium leprae in the state of São Paulo, an area of low-leprosy incidence in Brazil [PDF]

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2023
Background: Brazil has the second largest number of leprosy cases worldwide, and the state of São Paulo has been considered non-endemic since 2006. Methods: We analyzed 16 variable number tandem repeats loci and three single nucleotide polymorphisms ...
Amanda Juliane Finardi   +6 more
doaj   +1 more source

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