Results 21 to 30 of about 26,862 (225)

Desafios na era pós genômica para o desenvolvimento de testes laboratoriais para o diagnóstico da hanseníase Challenges in the post genomic era for the development of tests for leprosy diagnosis

Revista da Sociedade Brasileira de Medicina Tropical, 2008
O diagnóstico da hanseníase se baseia em manifestações clínicas e não existe teste laboratorial para diagnosticar casos assintomáticos ou para prever progressão da doença entre indivíduos expostos.
Mariane Martins de Araújo Stefani
doaj   +1 more source

A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]

, 2017
Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James, Madigan, Cressida A, Ramakrishnan, Lalita   +2 more
core   +2 more sources

Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. [PDF]

, 2003
Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection.
Cogen, Anna L, Lau, Helen Y, Monteleon, Christine L, Moore, Thomas A, Standiford, Theodore J   +4 more
core   +1 more source

The Findings of Mycobacterium Leprae DNA Existence in the Air as an Indication of Leprosy Transmission from Respiratory System

Jurnal Kesehatan Lingkungan, 2018
There are transmisions source in Infectious Leprosy Hospital Kediri from leprosy patients that can contaminate air with leprosy bacillus. There are also the risk groups, such as medical and non-medical staff, and visitors who contact with the environment.
Qotrunada Alam Cendaki
doaj   +1 more source

Validation of qPCR Methods for the Detection of Mycobacterium in New World Animal Reservoirs. [PDF]

PLoS Neglected Tropical Diseases, 2015
Zoonotic pathogens that cause leprosy (Mycobacterium leprae) and tuberculosis (Mycobacterium tuberculosis complex, MTBC) continue to impact modern human populations.
Genevieve Housman, Joanna Malukiewicz, Vanner Boere, Adriana D Grativol, Luiz Cezar M Pereira, Ita de Oliveira Silva, Carlos R Ruiz-Miranda, Richard Truman, Anne C Stone   +8 more
doaj   +1 more source

Global analyses of TetR family transcriptional regulators in mycobacteria indicates conservation across species and diversity in regulated functions [PDF]

, 2015
BACKGROUND: Mycobacteria inhabit diverse niches and display high metabolic versatility. They can colonise both humans and animals and are also able to survive in the environment.
A Mitchell, AA Alatoom, AJ Pompeani, AM McGuire, Ashima Singla, C Cole, D Goeke, F Frenois, F Frenois, G Beckers, J Engohang-Ndong, JA Ibarra, JD Thompson, JE Galagan, JR Bolla, K Rutherford, L Aravind, L Cuthbertson, L Cuthbertson, L Liu, L McMurry, LG Dover, M de la Paz Santangelo, M Weigoldt, MA Behr, MA Schumacher, Mahmudul Hasan Sikder, Mike Withers, MP Santangelo, NK Dutta, NM Nesbitt, P Golby, R Brosch, R Geize Van der, Ricardo J. C. Balhana, RJ Balhana, S Hirano, S Moller, Sharon L. Kendall, SK Ahn, SL Kendall, SL Kendall, TC Galvao, TL Bailey, V Vindal, Z Yu   +45 more
core   +3 more sources

Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis

Frontiers in Cellular and Infection Microbiology, 2021
Upon infection, Mycobacterium leprae, an obligate intracellular bacillus, induces accumulation of cholesterol-enriched lipid droplets (LDs) in Schwann cells (SCs). LDs are promptly recruited to M.
Thabatta L. S. A. Rosa, Maria Angela M. Marques, Zachary DeBoard, Kelly Hutchins, Carlos Adriano A. Silva, Christine R. Montague, Tianao Yuan, Julio J. Amaral, Georgia C. Atella, Patrícia S. Rosa, Katherine A. Mattos, Brian C. VanderVen, Ramanuj Lahiri, Nicole S. Sampson, Patrick J. Brennan, John T. Belisle, Maria Cristina V. Pessolani, Marcia Berrêdo-Pinho   +17 more
doaj   +1 more source

Métodos tintoriais utilizados na identificação do Mycobacterium leprae: revisão histológica Staining methods used in the identification of Mycobacterium leprae: historical review

Revista de Saúde Pública, 1984
Foi feita revisão histórica sobre métodos tintoriais utilizados na identificação baciloscópica do Mycobacterium leprae. Ao lado da descrição de cada método, e suas variantes, é feita extensa revisão bibliográfica.A historical review of the staining ...
Luiz Fernando de Góes Siqueira, Regina Gomes de Almeida, Walter Belda   +2 more
doaj   +1 more source

Clinical, histopathological, and molecular characterization of leprosy in an endemic area of the colombian caribbean

International Journal of Mycobacteriology, 2021
Background: Mycobacterium leprae was considered the only causal agent of leprosy until Mycobacterium lepromatosis was identified' which it has been suggested has greater pathogenicity and is linked to diffuse lepromatous leprosy (DLL) and Lucio's ...
Maria Carolina Fragozo-Ramos, Eder Cano-Pérez, Rita Magola Sierra-Merlano, Francisco Camacho-Chaljub, Doris Gómez-Camargo   +4 more
doaj   +1 more source

Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]

, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam, Kerber, Sarah, Pluschke, Gerd, Zimmer, Gert   +3 more
core   +3 more sources