Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic. [PDF]
, 2014 BACKGROUND: Leprosy has afflicted humankind throughout history leaving evidence in both early texts and the archaeological record. In Britain, leprosy was widespread throughout the Middle Ages until its gradual and unexplained decline between the 14th ...
Cole, ST +12 more
core +10 more sources
Avaliação da reação de mitsuda em pacientes virchovianos inativos antes e após imunoterapia
Revista da Sociedade Brasileira de Medicina Tropical, 1995 Neste estudo investigou-se o potencial imunomodulador do levamisole e da mistura BCG/Mycobacterium leprae em pacientes virchovianos inativos, utilizando como parâmetro a reação de Mitsuda.
Maria Sueli Parreira de Arruda +4 more
doaj +3 more sources
Sero-epidemiology as a tool to screen populations for exposure to Mycobacterium ulcerans [PDF]
, 2012 BACKGROUND: Previous analyses of sera from a limited number of Ghanaian Buruli ulcer (BU) patients, their household contacts, individuals living in BU non-endemic regions as well as European controls have indicated that antibody responses to the M ...
Yeboah-Manu, D. +10 more
core +1 more source
Frontiers in Microbiology, 2018 Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of ...
Diana Machado +13 more
doaj +1 more source
Fecal Excretion of Mycobacterium leprae, Burkina Faso
Emerging Infectious Diseases, 2021 Mycobacterium leprae was detected by optical microscopy, fluorescent in situ hybridization, and molecular detection in feces collected for the diagnosis of Entamoeba coli enteritis in a leprosy patient in Burkina Faso.
Anselme Millogo +5 more
doaj +1 more source
Evolution and expansion of the PE and PPE multigene families and their association with the duplication of the ESAT-6 () gene cluster regions [PDF]
, 2006 Background The PE and PPE multigene families of Mycobacterium tuberculosis comprise about 10% of the coding potential of the genome. The function of the proteins encoded by these large gene families remains unknown, although they have been proposed to be
Hyeyoung Lee +5 more
core +2 more sources
Mycobacterial Phylogenomics: An Enhanced Method for Gene Turnover Analysis Reveals Uneven Levels of Gene Gain and Loss among Species and Gene Families [PDF]
, 2014 Species of the genus Mycobacterium differ in several features, from geographic ranges, and degree of pathogenicity, to ecological and host preferences. The recent availability of several fully sequenced genomes for a number of these species enabled the ...
Kolokotronis, S. O. +4 more
core +2 more sources
Skin microbiota: a source of disease or defence?
, 2008 Microbes found on the skin are usually regarded as pathogens, potential pathogens or innocuous symbiotic organisms. Advances in microbiology and immunology are revising our understanding of the molecular mechanisms of microbial virulence and the specific
Cogen, AL, Gallo, RL, Nizet, V
core +1 more source
Widespread nasal carriage of Mycobacterium lepraeamong a healthy population in a hyperendemic region of northeastern Brazil. [PDF]
, 2015 A case-control study was conducted to determine the presence ofMycobacterium lepraeDNA in nasal secretions of leprosy cases and nonleprosy individuals in Fortaleza, Brazil.
Almeida, Rosa Livia Freitas +8 more
core +4 more sources
Mycobacterium leprae genomes from naturally infected nonhuman primates.
PLoS Neglected Tropical Diseases, 2018 Leprosy is caused by the bacterial pathogens Mycobacterium leprae and Mycobacterium lepromatosis. Apart from humans, animals such as nine-banded armadillos in the Americas and red squirrels in the British Isles are naturally infected with M.
Tanvi P Honap +9 more
doaj +1 more source