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Metabolomics of Mycobacterium tuberculosis
2015Enzymes fuel the biochemical activities of all cells. Their substrates and products thus offer a potential window into the physiologic state of a cell. Metabolomics focuses on the global, or systems-level, study of small molecules in a given biological system and thus provided an experimental tool with which to study cellular physiology on a global ...
Madhumitha, Nandakumar +3 more
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Mycobacterium tuberculosis – The Organism
2008The question of whether tuberculosis was due to a transmissible agent or to an inherited disposition was a subject of controversy in the nineteenth century, but the 1868 demonstration by Jean Antoine Villemin that inoculation of tuberculous material from humans and cattle into rabbits elicited characteristic granulomatous lesions swung the argument ...
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Transmission of Mycobacterium Tuberculosis
Journal of The Association of Physicians of IndiaTuberculosis (TB) has been a leading killer of mankind since time immemorial. There are four key components in the TB elimination approach. They are known as "Detect-Treat-Prevent-Build". Under the preventive strategy, scaling up of airborne infection control measures is an important step in controlling the global disease burden.This is a narrative ...
Malay, Sarkar, Jasmine, Sarkar
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Evolution of Mycobacterium tuberculosis
2013Genomic studies have provided a refined understanding of the genetic diversity within the Mycobacterium genus, and more specifically within Mycobacterium tuberculosis. These results have informed a new perspective on the macro- and micro-evolution of the tubercle bacillus. In the first step, a M. kansasii-like opportunistic pathogen acquired new genes,
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Ecology and evolution of Mycobacterium tuberculosis
Nature Reviews Microbiology, 2018S. Gagneux
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Genetic Diversity in Mycobacterium tuberculosis
2013Recent years have witnessed an increased appreciation of the extent and relevance of strain-to-strain variation in Mycobacterium tuberculosis. This paradigm shift can largely be attributed to an improved understanding of the global population structure of this organism, and to the realisation that the various members of the M.
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Tuberculosis (TB) remains the leading cause of death among infectious diseases, with 1.25 million fatalities reported globally in 2023. The World Health Organization estimates that 10.8 million individuals developed TB in the same year, with Southeast Asia and Africa accounting for the majority of cases. Despite low TB incidence rates overall in Canada,
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[Identification of Mycobacterium and Mycobacterium tuberculosis].
Problemy tuberkuleza, 1991The identification results of 3530 Mycobacterium strains isolated from a clinical material from tuberculosis patients are presented. 3219 (91.17%) of the strains are classified AS M. tuberculosis and 331 (8.83%) as nontuberculous, containing, generally, M. fortuitum group. (96 or 2.71% of the cases).
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