Results 91 to 100 of about 7,057 (208)

In silico structure-based drug screening of novel antimycobacterial pharmacophores by DOCK-GOLD tandem screening

International Journal of Mycobacteriology, 2017
Background: Enzymes responsible for cell wall development in Mycobacterium tuberculosis are considered as potential targets of anti-tuberculosis (TB) agents.
Junichi Taira, Takashi Ito, Hitomi Nakatani, Tomohiro Umei, Hiroki Baba, Shotaro Kawashima, Taira Maruoka, Hideyuki Komatsu, Hiroshi Sakamoto, Shunsuke Aoki   +9 more
doaj   +1 more source

Biophysical Interaction Landscape of Mycobacterial Mycolic Acids and Phenolic Glycolipids with Host Macrophage Membranes. [PDF]

ACS Appl Bio Mater, 2023
Srivatsav AT, Kapoor S.
europepmc   +1 more source

Mycolic acid-containing bacteria activate heterologous secondary metabolite expression in Streptomyces lividans [PDF]

, 2015
Hiroyasu Onaka, Taro Ozaki, Yukiko Mori, Masumi Izawa, Shohei Hayashi, Shumpei Asamizu   +5 more
openalex   +1 more source

Application of Monoclonal Anti-Mycolate Antibodies in Serological Diagnosis of Tuberculosis

Tropical Medicine and Infectious Disease
Patient loss to follow-up caused by centralised and expensive diagnostics that are reliant on sputum is a major obstacle in the fight to end tuberculosis. An affordable, non-sputum biomarker-based, point-of-care deployable test is needed to address this.
Alma Truyts, Ilse Du Preez, Eldas M. Maesela, Manfred R. Scriba, Les Baillie, Arwyn T. Jones, Kevin J. Land, Jan A. Verschoor, Yolandy Lemmer   +8 more
doaj   +1 more source

Molecular Docking Study on Phytochemicals of Alpinia galanga and Their Derivatives as Inhibitors of β-Ketoacyl Reductase (MabA) of Mycobacterium Tuberculosis: An In-silico Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Tuberculosis (TB), an infectious disease caused by the bacterium Mycobacterium Tuberculosis (MTB), continues to be a global health problem. Alpinia galanga (Linn.) of the Zingiberaceae family has antitubercular properties, and their mode of
Palaneswamy savetha, Ethirajulu Premalatha, Tanjavur Kaderesan Veerappan Sharavanan, Belukurichi Sadasivam Sangeetha, Iyanar Kannan   +4 more
doaj   +1 more source

Phylogeny of mycolic acid-containing actinomycetes

Journal of Industrial Microbiology & Biotechnology, 1996
Almost-complete 16S rRNA sequences of 32 representatives of the generaCorynebacterium, Gordona, Mycobacterium, Nocardia, Rhodococcus, Tsukamurella andTuricella were examined using the neighbor-joining, Fitch-Margoliash, maximum parsimony and maximum likelihood methods in order to clarify the suprageneric relationships of these taxa. The topology of the
J Chun, S-O Kang, Y C Hah, M Goodfellow
openaire   +1 more source

Comparative chemotaxonomic studies of mycolic acid-free coryneform bacteria of human origin [PDF]

, 1993
C Barreau, F. Bimet, M. Kiredjian, N. Rouillon, Chantal Bizet   +4 more
openalex   +1 more source

TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation. [PDF]

Nat Commun, 2021
Iizasa E, Chuma Y, Uematsu T, Kubota M, Kawaguchi H, Umemura M, Toyonaga K, Kiyohara H, Yano I, Colonna M, Sugita M, Matsuzaki G, Yamasaki S, Yoshida H, Hara H.   +14 more
europepmc   +1 more source

Engineering Mycobacterium smegmatis to produce oxygenic mycolic acids of Mycobacterium tuberculosis

Frontiers in Chemical Biology
Mycolic acids (MAs), which are β-hydroxy fatty acids with long alpha-alkyl side chains, are major components of the cell wall of Mycobacterium tuberculosis (Mtb), which causes tuberculosis. These lipids also occur in M.
Udipta Bohara, Udipta Bohara, Udipta Bohara, Liwu Li, Liwu Li, Biswarup Mukhopadhyay, Biswarup Mukhopadhyay, Biswarup Mukhopadhyay, Endang Purwantini   +8 more
doaj   +1 more source

Effect of Isoniazid on the In Vivo Mycolic Acid Synthesis, Cell Growth, and Viability of Mycobacterium tuberculosis

, 1972
Kuni Takayama, Wang Lynn, Hugo L. David
openalex   +2 more sources