Results 171 to 180 of about 7,057 (208)
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The major mycolic acids of Mycobacterium smegmatis
Progress in Lipid Research, 1982Mycolic acids derived from the cell wall of Mycobacterium smegmatis have been fractionated as their phenacyl esters by high performance liquid chromatography. Chromatography on a lo-pm particle size silica gel column resulted in the isolation of two minor (A and D) and two major (B and C) components.
G R, Gray, M Y, Wong, S J, Danielson
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A re-investigation of the mycolic acids of Mycobacterium avium
Chemistry and Physics of Lipids, 2020Mycolic acid methyl esters were extracted from Mycobacterium avium by a mild saponification protocol, designed to preserve labile components. The resulting mixture of α-, keto- and wax ester mycolates was accompanied by some degraded ω-carboxymycolic acid dimethyl esters, whose overall structures were found to support previous studies.
Alison, Jones +4 more
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The mycolic acids of Mycobacterium phlei
Journal of the Chemical Society, Chemical Communications, 1972The mycolic acids from Mycobacterium phlei consist of homologous series of various keto- and carboxymycolic acids in addition to those containing the β-hydroxy-acid system as sole oxygen functions.
K. Kusamran, N. Polgar, D. E. Minnikin
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Mycolic acids of Mycobacterium aurum
European Journal of Biochemistry, 1988Mycobacterium aurum (type strain) was analyzed for its mycolate content. Three types of mycolates were identified: di‐unsaturated, oxo and dicarboxy mycolates, each type being constituted by two subtypes. The acid released by pyrolysis was identified as docosanoic acid.
M A, Lanéelle +3 more
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Mycolic acids for the control of tuberculosis
Expert Opinion on Therapeutic Patents, 2007Mycobacterium tuberculosis, the causative agent of tuberculosis, is on the rise again in step with the HIV/AIDS pandemic. Characteristically, M. tuberculosis features a hydrophobic cell envelope conferring resistance to degradation by host defences and impeding drug entry. This review focuses on mycolic acids, the distinctive cornerstone lipids of that
Gianna Sekanka +3 more
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The Mycolic Acids of Mycobacterium chitae
Microbiology, 1985Summary: Two-dimensional thin-layer chromatography of whole-organism acid methanolysates of Mycobacterium chitae gives a characteristic pattern composed of -mycolate, a lower molecular weight -mycolate and characteristic pairs of polar mycolates. Analysis of alkaline methanolysates confirmed that these polar mycolates were derived from epoxymycolic ...
V. AUSINA, M. LUQUIN, L. MARGARIT
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Tetrahedron, 2014
Abstract We report the synthesis of single enantiomers of epoxy-mycolic acids containing an α-methyl- trans -alkene or a cis -cyclopropane with structures that match those of major isomers of such molecules present in complex mixtures in Mycobacteria such as Mycobacterium fortuitum or Mycobacterium ...
Dakhil Z. Al Kremawi +2 more
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Abstract We report the synthesis of single enantiomers of epoxy-mycolic acids containing an α-methyl- trans -alkene or a cis -cyclopropane with structures that match those of major isomers of such molecules present in complex mixtures in Mycobacteria such as Mycobacterium fortuitum or Mycobacterium ...
Dakhil Z. Al Kremawi +2 more
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Mycolic acid patterns of some species of Mycobacterium
Archives of Microbiology, 1984Representative strains of some species of Mycobacterium were degraded by both acid and alkaline methanolysis. Two-dimensional thin-layer chromatography was used to determine the patterns of mycolic acids and other long-chain components in these methanolysates. Patterns composed of alpha-, methoxy- and ketomycolates were found in Mycobacterium asiaticum,
D E, Minnikin +4 more
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Apoptosis Modulation by Mycolic Acid, Tuberculostearic Acid and Trehalose 6,6′-Dimycolate
Journal of Infection, 2002The object of our study is to demonstrate that some components of M. tuberculosis, such as cord factor or mycolic acid or whole bacteria can prolong cell survival compared to controls. The cells treated with cord factor or mycolic acid at a concentration of 5 microg/ml were 65+/-8% viable reaching 70+/-8% at a concentration of 10 microg/ml.
I. NUZZO +4 more
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