Results 101 to 110 of about 127,348 (379)
Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]
, 2004 Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Friedrich, N. +5 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah +8 more
wiley +1 more source
Safety and effectiveness of mycophenolate in systemic sclerosis. A systematic review.
PLoS ONE, 2015 BackgroundMycophenolate is increasingly being used in the rheumatic diseases. Its main adverse effects are gastrointestinal, myelosuppression, and infection.
Mohammed A Omair +2 more
doaj +1 more source
Mycophenolate-induced Colitis: A Case Report with Focused Review of Literature [PDF]
, 2020 Rehan Farooqi +2 more
openalex +1 more source
Advanced Science, EarlyView.T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu +14 more
wiley +1 more source
Idiopathic membranoproliferative glomerulonephritis treated with mycophenolate mofetil
Clinical Case Reports, 2018 Key Clinical Message “Idiopathic” membranoproliferative glomerulonephritis (MPGN) is rare compared to secondary forms and usually a progressive disease.
Abhilash Koratala +3 more
doaj +1 more source
Assessment of tissue fibrosis in skin biopsies from patients with systemic sclerosis employing confocal laser scanning microscopy: an objective outcome measure for clinical trials? [PDF]
, 2010 OBJECTIVES: To obtain an objective, unbiased assessment of skin fibrosis in patients with SSc for use in clinical trials of SSc disease-modifying therapeutics.
Busquets, Joanna +3 more
core +3 more sources
Annals of Gastroenterological Surgery, EarlyView.In a single‐center cohort of 577 adult LDLT recipients who underwent simultaneous splenectomy, clinically significant SFSS grade B/C (ILTS‐iLDLT‐LTSI 2023) occurred in 18.2% and was associated with inferior graft survival. Multivariate analysis identified MELD ≥ 30, NLR ≥ 4.5, and donor age ≥ 50 years as independent risk factors, which risk rising ...
Kyohei Yugawa +6 more
wiley +1 more source