Results 251 to 260 of about 127,348 (379)

Clinical profiles associated with rapidly progressive interstitial lung disease in antisynthetase syndrome: A multicentric cohort study (TYPASS study)

Journal of Internal Medicine, EarlyView.
Abstract Objectives To assess factors associated with rapidly progressive interstitial lung disease (ILD) (RP‐ILD) at time of ILD diagnosis in a multicentric retrospective cohort study of antisynthetase syndrome (ASyS). We used a complementary unsupervised approach, hierarchical clustering, to delineate distinct phenotypes among ASyS patients with ILD.
Maxime Billotte, Thomas Moulinet, Alain Meyer, Houda Camara, Loïs Bolko, Kévin Didier, Sandra Dury, Bernard Bonnotte, Hervé Devilliers, Philippe Bonniaud, Guillaume Beltramo, Julien Campagne, Nadine Magy‐Bertrand, Aurore Chaudier, Simon Valentin, Roland Jaussaud, Paul Decker   +16 more
wiley   +1 more source

An intact microbiota is required for the gastrointestinal toxicity of the immunosuppressant mycophenolate mofetil.

The Journal of Heart and Lung Transplantation, 2018
K. Flannigan, Michael R. Taylor, Sheldon K. Pereira, J. Rodriguez-Arguello, Andrew Moffat, L. Alston, Xuemei Wang, Karen Poon, P. Beck, K. Rioux, Mahesh Jonnalagadda, P. Chelikani, H. Galipeau, I. Lewis, M. Workentine, S. Greenway, S. Hirota   +16 more
semanticscholar   +1 more source

Mucoadhesive Drug Delivery Systems for Oral Chronic Inflammatory Mucosal Diseases. The Future is Already Present. A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Background Oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS) are considered the most painful oral inflammatory diseases, with high global prevalence and significant impacts on patients' quality of life. In the last decades, researchers have been exploring mucoadhesive drug delivery systems (MDDS) to improve drugs safety and ...
M. E. Mauceri, M. Coppini, V. De Caro, G. Di Prima, R. Mauceri, V. Panzarella, G. Giuliana, G. Campisi   +7 more
wiley   +1 more source

A Challenging Case of MOG-Associated Optic Neuritis: The Role of IL-6 Inhibition in Refractory Disease. [PDF]

Int Med Case Rep J
Alnajashi H, Alnahdi M.
europepmc   +1 more source

Manifestation of morphea in a patient with myasthenia gravis under therapy with zilucoplan

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Phoebe Wellmann, Jana Zschüntzsch, Michael P. Schön, Rotraut Mössner   +3 more
wiley   +1 more source

Impact of Dental Status on Heart Transplantation Outcomes

Oral Diseases, EarlyView.
ABSTRACT Objective Oral infections and poor dental health may contribute to systemic complications after heart transplantation, yet data on their impact is limited. In the absence of standardized dental guidelines for transplant candidates, this study evaluated preoperative dental status and its association with post‐transplant outcomes.
Katharina Theresa Obermeier, Ina Dewenter, Maximilian Vorstandlechner, Maximilian Geyer, Wenko Smolka, Christine Kamla, Madeleine Orban, Christoph S. Mueller, Anusha Abdullah   +8 more
wiley   +1 more source

Curious Coexistence of Perivascula Epitheloid Cell Tumour (PEComa) Systemic Sclerosis-Associated Interstitial Lung Disease and Biopsy-Proven Lymphangioleiomyomatosis in a Middle-Aged Female: A Case Report. [PDF]

Cureus
Isse S, Shafiq I, Dimashkieh H, Quadri A, Khan S.   +4 more
europepmc   +1 more source

Janus Kinase Inhibitors for the Treatment of Pediatric Morphea: A Systematic Review

Pediatric Dermatology, EarlyView.
ABSTRACT Morphea, also known as localized scleroderma (LoS), is an inflammatory, fibrosing dermatologic disorder of the skin and underlying tissues with associated comorbidities including joint contractures, limb‐length discrepancies, and inflammatory arthropathy occurring more commonly in children.
Alexa Moschella, Celina DeBiasio, Carmen Liy‐Wong   +2 more
wiley   +1 more source

Steroid-Refractory Cholestatic Immune-Mediated Hepatitis Following Nivolumab Therapy in an Elderly Patient with Metastatic Melanoma: A Rare and Challenging Presentation. [PDF]

Curr Oncol
Posado-Dominguez L, Feito-Perez J, Escribano-Iglesias M, Bragado Pascual M, Fonseca Sánchez E.   +4 more
europepmc   +1 more source

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source