Results 321 to 330 of about 127,348 (379)

Reducing Immunogenicity of Pegloticase With Concomitant Use of Mycophenolate Mofetil in Patients With Refractory Gout: A Phase II, Randomized, Double‐Blind, Placebo‐Controlled Trial

Arthritis & Rheumatology, 2021
Pegloticase is used for the treatment of severe gout, but its use is limited by immunogenicity. This study was undertaken to evaluate whether mycophenolate mofetil (MMF) prolongs the efficacy of pegloticase.
P. Khanna   +16 more
semanticscholar   +1 more source

Mycophenolate Mofetil

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1997
Mycophenolate mofetil is the morpholinoethylester prodrug of mycophenolic acid, an agent that inhibits the proliferation of B and T lymphocytes through noncompetitive, reversible inhibition of inosine monophosphate dehydrogenase, a key enzyme in the de novo synthetic pathway of guanine nucleotides.
T M, Sievers   +6 more
openaire   +2 more sources

Systematic review with meta‐analysis: mycophenolate mofetil as a second‐line therapy for autoimmune hepatitis

Alimentary Pharmacology and Therapeutics, 2019
First‐line treatment for autoimmune hepatitis (AIH) typically includes corticosteroids in combination with azathioprine. Mycophenolate mofetil (MMF) is often used as a rescue therapy in patients who are intolerant of, or nonresponsive to, standard ...
Priscila Santiago   +3 more
semanticscholar   +1 more source

Mycophenolate mofetil

Dermatologic Therapy, 2007
Mycophenolate mofetil (MMF) is a relatively new systemic immunosuppressive agent whose use is rapidly increasing within the field of dermatologic. Originally used in the 1970s for the treatment of psoriasis, MMF has demonstrated efficacy in multiple types of inflammatory skin diseases.
Jeffrey, Zwerner, David, Fiorentino
openaire   +2 more sources

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