Results 41 to 50 of about 127,348 (379)

Mycophenolate revisited [PDF]

Transplant International, 2015
The patent of mycophenolate mofetil (MMF) has expired, and for enteric-coated mycophenolate sodium (EC-MPS), this will happen in 2017. In the twenty years these drugs have been used, they have become extremely popular. In this review, the reasons for the popularity of mycophenolate are discussed, including the benefits compared to azathioprine. MMF and
Gelder, Teun, Hesselink, Dennis
openaire   +2 more sources

What have we learned about primary liver transplantation under tacrolimus immunosuppression? - Long-term follow-up of the first 1000 patients [PDF]

, 1999
Objective: To summarize the long-term efficacy and safety of tacrolimus in orthotopic liver transplant (OLT) recipients, as well as to examine the factors that influence long-term morbidity and mortality rates. Background: Tacrolimus (FK506, Prograf) was
Abu-Elmagd, K, Fung, J, Jain, A, Kashyap, R, Reyes, J, Rohal, S, Starzl, T   +6 more
core   +2 more sources

Effect of Corticosteroid-Sparing Treatment With Mycophenolate Mofetil vs Methotrexate on Inflammation in Patients With Uveitis: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Methotrexate and mycophenolate mofetil are commonly used immunomodulatory therapies for achieving corticosteroid-sparing control of noninfectious uveitis, but there is uncertainty about which drug is more effective.
S. Rathinam, J. Gonzales, Radhika Thundikandy, Anuradha V. Kanakath, S. Murugan, R. Vedhanayaki, L. Lim, E. Suhler, H. Al-Dhibi, T. Doan, J. Keenan, Maya M. Rao, Caleb D. Ebert, Hieu H. Nguyen, Eric Kim, T. Porco, N. Acharya   +16 more
semanticscholar   +1 more source

Renal function at 12 months of kidney transplantation comparing tacrolimus and mycophenolate with tacrolimus and mTORi in donors with different KDPI ranges. A multicenter cohort study using propensity scoring

Frontiers in Transplantation, 2023
IntroductionThe combination of tacrolimus/mTORi compared to tacrolimus/mycophenolate (MMF) was shown to be safe in the TRANSFORM trial. For donors with a high KDPI (Kidney Donor Profile Index), however, there are no data to support the effectiveness of ...
Arlisson Macedo Rodrigues, Mariana Tavares Tanno, Mariana Moraes Contti, Hong Si Nga, Mariana Farina Valiatti, Silvana Daher Costa, Tainá Veras de Sandes-Freitas, Ronaldo de Matos Esmeraldo, Camila Marinho Assunção, Juliana Bastos Campos Tassi, Gustavo Fernandes Ferreira, Claudia Rosso Felipe, Jose Osmar Medina Pestana, Helio Tedesco Silva, Luis Gustavo Modelli de Andrade   +14 more
doaj   +1 more source

Rituximab monitoring and redosing in pediatric neuromyelitis optica spectrum disorder. [PDF]

, 2016
OBJECTIVE: To study rituximab in pediatric neuromyelitis optica (NMO)/NMO spectrum disorders (NMOSD) and the relationship between rituximab, B cell repopulation, and relapses in order to improve rituximab monitoring and redosing.
Alper, G, Appleton, R, Banwell, B, Benson, La, Brilot, F, Dale, R. C., Deiva, K, Gorman, Mp, Leventer, Rj, Mohammad, Ss, Nolan, M, Nosadini, M, Ramanathan, S, Riney, Cj, Waldman, At   +14 more
core   +1 more source

Vancomycin relieves mycophenolate mofetil–induced gastrointestinal toxicity by eliminating gut bacterial β-glucuronidase activity

Science Advances, 2019
Toxicity from the immunosuppressant mycophenolate mofetil is prevented by eliminating gut bacteria expressing β-glucuronidase. Mycophenolate mofetil (MMF) is commonly prescribed and has proven advantages over other immunosuppressive drugs.
Michael R. Taylor, K. Flannigan, Hannah Rahim, Amina Mohamud, I. Lewis, S. Hirota, S. Greenway   +6 more
semanticscholar   +1 more source

Eosinophilic granulomatosis with polyangiitis (EGPA) on remission with a new neuropathy: a rare case of mycophenolate induced primary CNS lymphoproliferative disease

Journal of Community Hospital Internal Medicine Perspectives, 2020
Introduction Mycophenolate Mofetil (MMF), although a widely used immunosuppressant; an increasing concern of MMF induced Primary Central Nervous System Lymphoma (PCNSL) are being reported.
Pragya Shrestha, Ian Garrahy, Shoja Rahimian   +2 more
doaj   +1 more source

Safety and efficacy of mycophenolate in COVID-19: a nonrandomised prospective study in western IndiaResearch in context

The Lancet Regional Health - Southeast Asia, 2023
Summary: Background: Antivirals and immunosuppressive agents are used with variable success in the treatment of COVID-19. Mycophenolate, an inhibitor of enzyme inosine monophosphate dehydrogenase, is an immunosuppressant used to prevent allograft ...
Atul Sajgure, Ajit Kulkarni, Atul Joshi, Vasanti Sajgure, Vaishali Pathak, Rashida Melinkeri, Shilpa Pathak, Sumit Agrawal, Manoj Naik, Milind Rajurkar, Ameya Sajgure, Girish Date   +11 more
doaj   +1 more source

SAT-429 Systemic Safety Analysis of Mycophenolate in Graves’ Orbitopathy

Journal of the Endocrine Society, 2020
Context The dual antiproliferative mechanism of mycophenolate appears to be beneficial in Graves’ orbitopathy (GO). Methods The safety data, which is of utmost importance in immunomodulation, from the two major randomized mycophenolate trials [“Chinese ...
A. C. H. Lee, T. Diana, L. Frommer, G. Kahaly   +3 more
semanticscholar   +1 more source

Analysis of the Clinical Effects of the Combination of Mycophenolate Mofetil with Either Tacrolimus or Cyclophosphamide [PDF]

Clinics, 2020
OBJECTIVES: Here, we aimed to compare the clinical effects of mycophenolate mofetil combined with either tacrolimus or with cyclophosphamide on lupus nephritis (LN) and to analyze their influence on the expression of cystatin C and on transforming growth
Xuebing Zhang, Pei Liu, Zhen Zhang
doaj   +1 more source