Results 51 to 60 of about 127,348 (379)

A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [PDF]

, 2019
Background The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was first described in 2012 and attracted a great international attention due to multiple healthcare associated outbreaks.
Al-Ali, Anfal Y., Al-Tawfiq, Jaffar A., Momattin, Hisham   +2 more
core   +1 more source

A Tissue-Tended Mycophenolate-Modified Nanoparticle Alleviates Systemic Lupus Erythematosus in MRL/Lpr Mouse Model Mainly by Promoting Local M2-Like Macrophagocytes Polarization

International Journal of Nanomedicine, 2022
Biling Jiang,1,* Yamin Zhang,1,* Yuce Li,2 Yu Chen,2 Shanshan Sha,1 Liang Zhao,1 Danqi Li,1 Jingjing Wen,1 Jiajia Lan,1 Yuchen Lou,1 Hua Su,3 Chun Zhang,3 Jintao Zhu,2 Juan Tao1 1Hubei Engineering Research Center of Skin Disease Theranostics and ...
Jiang B, Zhang Y, Li Y, Chen Y, Sha S, Zhao L, Li D, Wen J, Lan J, Lou Y, Su H, Zhang C, Zhu J, Tao J   +13 more
doaj  

Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder [PDF]

, 2019
Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).
Alexander, Tobias, Asseyer, Susanna, Bellmann-Strobl, Judith, Hauser, Anja E., Koppen, Sofie van, Lindquist, Randall L., Mothes, Ronja, Niesner, Raluca A., Ostendorf, Lennard, Paul, Friedemann, Radbruch, Helena, Ruprecht, Klemens   +11 more
core   +3 more sources

An Analysis of Early Renal Transplant Protocol Biopsies - the High Incidence of Subclinical Tubulitis [PDF]

, 2001
To investigate the possibility that we have been underestimating the true incidence of acute rejection, we began to perform protocol biopsies after kidney transplantation. This analysis looks at the one-week biopsies. Between March 1 and October 1, 1999,
Burdick, D'Ardenne, Hanas, Kjellstrand, Racusen, Randhawa, Rush, Rush, Rush, Saad, Seron, Shapiro, Shapiro, Shapiro, Shapiro, Solez, Starzl   +16 more
core   +1 more source

NF-κB Inhibitors Attenuate MCAO Induced Neurodegeneration and Oxidative Stress—A Reprofiling Approach

Frontiers in Molecular Neuroscience, 2020
Stroke is the leading cause of morbidity and mortality worldwide. About 87% of stroke cases are ischemic, which disrupt the physiological activity of the brain, thus leading to a series of complex pathophysiological events. Despite decades of research on
Awais Ali, Fawad Ali Shah, Alam Zeb, Imran Malik, Arooj Mohsin Alvi, Lina Tariq Alkury, Sajid Rashid, Ishtiaq Hussain, Najeeb Ullah, Najeeb Ullah, Arif Ullah Khan, Phil Ok Koh, Shupeng Li, Shupeng Li   +13 more
doaj   +1 more source

Alemtuzumab pre-conditioning with tacrolimus monotherapy in pediatric renal transplantation [PDF]

, 2007
We employed antibody pre-conditioning with alemtuzumab and posttransplant immunosuppression with low-dose tacrolimus monotherapy in 26 consecutive pediatric kidney transplant recipients between January 2004 and December 2005. Mean recipient age was 10.7 ±
Basu, A, Ellis, D, Erkan, E, Gray, EA, Grosso, MJ, James, G, Kayler, LK, Marcos, A, McFeaters, CG, Moritz, ML, Shapiro, R, Starzl, TE, Tan, HP, Vats, AN, Zeevi, A   +14 more
core   +1 more source

Simultaneous administration of adjuvant donor bone marrow in pancreas transplant recipients [PDF]

, 1999
Objective: The effect of donor bone marrow was evaluated for its potentially favorable effect in the authors' simultaneous pancreas/kidney transplant program.
Abdul S. Rao, Carlos A. Vivas, Corry, Corry, Corry, Corry, Corry, Egidi, Fioretto, Fontes, Greussner, Gruessner, Igor Dvorchik, John J. Fung, Jordan, Kapur, Mark L. Jordan, Nghiem, Pinna, Pradip K. Chakrabarti, Rao, Robert J. Corry, Ron Shapiro, Scantlebury, Shapiro, Sollinger, Starzl, Starzl, Starzl, Sugitani, Thomas E. Starzl, Tyden, Tyden, Velma P. Scantlebury, Wakely, Zehr   +35 more
core   +2 more sources

Failure to Preserve β-Cell Function With Mycophenolate Mofetil and Daclizumab Combined Therapy in Patients With New- Onset Type 1 Diabetes [PDF]

, 2010
OBJECTIVE This trial tested whether mycophenolate mofetil (MMF) alone or with daclizumab (DZB) could arrest the loss of insulin-producing β-cells in subjects with new-onset type 1 diabetes.
Gottlieb, Peter A., Greenbaum, Carla J., Krause-Steinrauf, Heidi, Lachin, John M., Moran, Antoinette M., Quinlan, Scott, Rodriguez, Henry, Schatz, Desmond A., Skyler, Jay S., Type 1 Diabetes TrialNet MMF/DZB Study Group, Wilson, Darrell M.   +10 more
core   +2 more sources

Mycophenolate Mofetil Versus Cyclophosphamide for the Induction of Remission in Nonlife-Threatening Relapses of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Randomized, Controlled Trial.

American Society of Nephrology. Clinical Journal, 2019
BACKGROUND AND OBJECTIVES Cyclophosphamide has been the mainstay of treatment of ANCA-associated vasculitis. However, cyclophosphamide has unfavorable side effects and alternatives are needed.
Janneke Tuin, P. Stassen, D. Bogdan, J. Broekroelofs, P. van Paassen, J. C. Cohen Tervaert, J. Sanders, C. Stegeman   +7 more
semanticscholar   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source