Results 1 to 10 of about 14,175 (232)
Mycophenolic Acid in Silage [PDF]
ABSTRACT We examined 233 silage samples and found that molds were present in 206 samples with counts between 1 × 10 3 and 8.9 × 10 7 (mean, 4.7 × 10 6 ) CFU/g. Mycophenolic acid, a metabolite of Penicillium roqueforti , was detected by
Isabell Schneweis+3 more
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Low-Frequency Raman Spectroscopy of Pure and Cocrystallized Mycophenolic Acid [PDF]
The aqueous solubility of solid-state pharmaceuticals can often be enhanced by cocrystallization with a coformer to create a binary cocrystal with preferred physical properties.
Catherine S. Wallace+2 more
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Treatment Of Psoriasis With Oral Mycophenolic Acid
Mycophenolic acid (MPA), an inhibitor of purine synthesis, was evaluated for its therapeutic and adverse effects in 29 patients with psoriasis. MPA was administered orally for at least 12 weeks, during which time the daily dose was increased from 1600 to 4800 mg depending on occurrence of adverse reactions.
E. Linn Jones+4 more
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Titer improvement of mycophenolic acid in the novel producer strain Penicillium arizonense and expression analysis of its biosynthetic genes [PDF]
Mycophenolic acid (MPA) is the active ingredient in the most important immunosuppressive pharmaceuticals. It has antifungal, antibacterial, antiviral, anti-psoriasis, and antitumor activities.
Hala A. Ammar+3 more
doaj +2 more sources
Mycophenolic Acid Is a Potent Inhibitor of Angiogenesis [PDF]
Angiogenesis is necessary for the vascularization of a tumor, providing essential nourishment for tumor growth, and the progression and metastasis of cancer cells.1 Although tremendous efforts and resources have been dedicated to discovering angiogenesis inhibitors, very few candidates have been approved by FDA for therapeutic applications. Currently,
Xinrong Wu+5 more
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INTRODUCTION: Development of chronic lung allograft dysfunction is a limiting factor for post-lung transplant survival. We evaluated whether the dose of the immunosuppressant mycophenolate mofetil or plasma concentrations of the active metabolite ...
Carolin Steinack+6 more
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Background and objectivesKidney transplant recipients are highly vulnerable to the serious complications of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infections and thus stand to benefit from vaccination.
Chukwuma A Chukwu+6 more
doaj +2 more sources
Seroconversion rates after COVID-19 vaccination are significantly lower in kidney transplant recipients compared to healthy cohorts. Adaptive immunization strategies are needed to protect these patients from COVID-19.
Louise Benning+23 more
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Therapeutic monitoring of mycophenolic acid in renal transplanted patients by a validated HPLC method [PDF]
Introduction: Mycophenolate mofetil and its active metabolite mycophenolic acid are routinely used as immunosuppressant drugs in solid organ transplantation in a fixed daily dose regimen in association with cyclosporine, tacrolimus and steroids ...
Mikaela Kolaci+4 more
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Analysis of mycophenolic acid from saliva samples after its purification with the method of solidliquid extraction [PDF]
Pharmacological effect of a drug depends on its free fraction in plasma. By certain drugs, like immunosupresive mycophenolic acid, concentrations below therapeutic lead to rejection of the transplanted organ while concentrations above therapeutic lead to
Otašević Biljana+5 more
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