Results 1 to 10 of about 14,175 (232)

Mycophenolic Acid in Silage [PDF]

open access: greenApplied and Environmental Microbiology, 2000
ABSTRACT We examined 233 silage samples and found that molds were present in 206 samples with counts between 1 × 10 3 and 8.9 × 10 7 (mean, 4.7 × 10 6 ) CFU/g. Mycophenolic acid, a metabolite of Penicillium roqueforti , was detected by
Isabell Schneweis   +3 more
openalex   +4 more sources

Low-Frequency Raman Spectroscopy of Pure and Cocrystallized Mycophenolic Acid [PDF]

open access: yesPharmaceutics, 2023
The aqueous solubility of solid-state pharmaceuticals can often be enhanced by cocrystallization with a coformer to create a binary cocrystal with preferred physical properties.
Catherine S. Wallace   +2 more
doaj   +2 more sources

Treatment Of Psoriasis With Oral Mycophenolic Acid

open access: bronzeJournal of Investigative Dermatology, 1975
Mycophenolic acid (MPA), an inhibitor of purine synthesis, was evaluated for its therapeutic and adverse effects in 29 patients with psoriasis. MPA was administered orally for at least 12 weeks, during which time the daily dose was increased from 1600 to 4800 mg depending on occurrence of adverse reactions.
E. Linn Jones   +4 more
openalex   +4 more sources

Titer improvement of mycophenolic acid in the novel producer strain Penicillium arizonense and expression analysis of its biosynthetic genes [PDF]

open access: yesBMC Microbiology, 2023
Mycophenolic acid (MPA) is the active ingredient in the most important immunosuppressive pharmaceuticals. It has antifungal, antibacterial, antiviral, anti-psoriasis, and antitumor activities.
Hala A. Ammar   +3 more
doaj   +2 more sources

Mycophenolic Acid Is a Potent Inhibitor of Angiogenesis [PDF]

open access: bronzeArteriosclerosis, Thrombosis, and Vascular Biology, 2006
Angiogenesis is necessary for the vascularization of a tumor, providing essential nourishment for tumor growth, and the progression and metastasis of cancer cells.1 Although tremendous efforts and resources have been dedicated to discovering angiogenesis inhibitors, very few candidates have been approved by FDA for therapeutic applications. Currently,
Xinrong Wu   +5 more
openalex   +4 more sources

Influence of mycophenolate mofetil dosage and plasma levels on the occurrence of chronic lung allograft dysfunction in lung transplants: a retrospective cohort analysis

open access: yesSwiss Medical Weekly, 2022
INTRODUCTION: Development of chronic lung allograft dysfunction is a limiting factor for post-lung transplant survival. We evaluated whether the dose of the immunosuppressant mycophenolate mofetil or plasma concentrations of the active metabolite ...
Carolin Steinack   +6 more
doaj   +1 more source

Evaluating the antibody response to SARS-COV-2 vaccination amongst kidney transplant recipients at a single nephrology centre.

open access: yesPLoS ONE, 2022
Background and objectivesKidney transplant recipients are highly vulnerable to the serious complications of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infections and thus stand to benefit from vaccination.
Chukwuma A Chukwu   +6 more
doaj   +2 more sources

Humoral response to SARS-CoV-2 mRNA vaccination in previous non-responder kidney transplant recipients after short-term withdrawal of mycophenolic acid

open access: yesFrontiers in Medicine, 2022
Seroconversion rates after COVID-19 vaccination are significantly lower in kidney transplant recipients compared to healthy cohorts. Adaptive immunization strategies are needed to protect these patients from COVID-19.
Louise Benning   +23 more
doaj   +1 more source

Therapeutic monitoring of mycophenolic acid in renal transplanted patients by a validated HPLC method [PDF]

open access: yesFolia Medica, 2021
Introduction: Mycophenolate mofetil and its active metabolite mycophenolic acid are routinely used as immunosuppressant drugs in solid organ transplantation in a fixed daily dose regimen in association with cyclosporine, tacrolimus and steroids ...
Mikaela Kolaci   +4 more
doaj   +3 more sources

Analysis of mycophenolic acid from saliva samples after its purification with the method of solidliquid extraction [PDF]

open access: yesArhiv za farmaciju, 2014
Pharmacological effect of a drug depends on its free fraction in plasma. By certain drugs, like immunosupresive mycophenolic acid, concentrations below therapeutic lead to rejection of the transplanted organ while concentrations above therapeutic lead to
Otašević Biljana   +5 more
doaj   +1 more source

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