Results 21 to 30 of about 14,175 (232)
Frontiers in Bioengineering and Biotechnology, 2021 Background: Titanium is commonly used in blood-exposed medical devices because it has superior blood compatibility. Mycophenolic acid inhibits the proliferation of vascular smooth muscle cells.
Jae Won Shim +26 more
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Journal of Pharmaceutical Analysis, 2014 A simple, sensitive and high throughput ultra performance liquid chromatography tandem mass spectrometry method has been developed for the determination of mycophenolic acid in human plasma.
Vivek Upadhyay +4 more
doaj +1 more source
Monitoring mycophenolic acid [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2002 The immunosuppressive agent mycophenolate mofetil is a prodrug for the active compound mycophenolic acid. Following organ transplantation, it is used mostly in combination with other immunosuppressive drugs, but it has also been used as primary therapy.
openaire +3 more sources
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Journal of Advanced Pharmaceutical Technology & Research, 2020 A reliable method has been validated using ultra-performance liquid chromatography mass spectrometry (MS)/MS for simultaneous evaluation of human plasma concentration of mycophenolic acid (MPA) and its major metabolites both total and free form.
Napatsanan Tanathitiphuwarat +6 more
doaj +1 more source
Practical Laboratory Medicine, 2017 Background: For TDM of mycophenolate acid (MPA), the Roche Total Mycophenolic Acid® assay based on the inhibition of recombinant inosine monophosphate dehydrogenase (IMPDH) has been shown to be a simple and reliable alternative to chromatographic methods.
François Parant +2 more
doaj +1 more source
Bacterial IMPDH Gene Used for the Selection of Mammalian Cell Transfectants
BioTechniques, 2003 Stable cell transfection is used for the expression of exogenous genes or cDNAs in eukaryotic cells. Selection of these transfectants requires a dominant selectable marker. A variety of such markers has been identified and is currently in use.
Mekhine Baccam, Eliezer Huberman
doaj +1 more source
Liposomal Delivery of Mycophenolic Acid With Quercetin for Improved Breast Cancer Therapy in SD Rats
Frontiers in Bioengineering and Biotechnology, 2020 The present study explores the influence of mycophenolic acid (MPA) in combination therapy with quercetin (QC) (impeding MPA metabolic rate) delivered using the liposomal nanoparticles (LNPs).
Gopal Patel +8 more
doaj +1 more source
Mycophenolic acid induces senescence of vascular precursor cells. [PDF]
PLoS ONE, 2018 OBJECTIVE:Endothelial dysfunction is central to the pathogenesis of many rheumatic diseases, typified by vascular inflammation and damage. Immunosuppressive drugs induce disease remission and lead to improved patient survival.
Ellen Go +9 more
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Mycophenolic acid induces apoptosis of hepatic stellate cells in an in vitro model of HCV
Annals of Hepatology, 2015 Introduction. Hepatitis C virus (HCV) infection is an important risk factor for the development of liver fibrosis and progression to cirrhosis. Liver transplantation as terminal treatment option for liver disease requires life-long immunosuppression ...
Jan Best +10 more
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