Results 31 to 40 of about 14,175 (232)
Mycotoxicological monitoring. Part 3. Feedstuffs from raw grain processing
Ветеринария сегодня, 2020 The paper presents the results of mycotoxicological testing of the production batches of sunflower cake and meal, feedstuffs of soybean and wheat bran processing received from domestic processing establishments and livestock farms from 2009 to 2019 ...
G. P. Kononenko +2 more
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Communications Biology, 2021 Guste Urbonaite and Jimmy Tsz Hang Lee et al. present a droplet-based single-cell sequencing method optimized for use in yeast. They use their method—yeastDropSeq—to investigate the changes in gene expression profiles following treatment with the ...
Guste Urbonaite +5 more
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The Lancet MicrobeSummary: Background: Pneumocystis pneumonia (PCP) case clusters involving solid organ transplant (SOT) recipients have been reported worldwide. Mycophenolic acid, an immunosuppressant used to prevent rejection in SOT recipients that targets the inosine ...
Claire V Hoffmann, PhD +63 more
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Mycotoxicological monitoring. Part 1. Complete mixed feed for pigs and poultry (2009–2018)
Ветеринария сегодня, 2020 Results of the ten-year annual mycotoxicological testing of complete mixed feeds for pigs and poultry submitted by holdings and processing establishments located in the Northwestern, Central, Southern, Volga and Ural Federal Districts are presented ...
G. P. Kononenko +2 more
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Kidney Transplantation for Erdheim-Chester Disease
Case Reports in Transplantation, 2020 Erdheim-Chester disease is a rare inflammatory disease that infiltrates skeletal and extra-skeletal tissue. Chronic kidney disease (CKD) in Erdheim-Chester disease is usually attributed to retroperitoneal lesions that lead to urologic obstruction and ...
Jongwon Yoo +8 more
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Acta Pharmaceutica Sinica B, 2019 Mycophenolic acid (MPA, 1) and its derivatives are first-line immunosuppressants used in organ transplantation and for treating autoimmune diseases. Despite chemical synthetic achievements, the biosynthetic formation of a seven-carbon carboxylic acid ...
Xiwei Chen +6 more
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ANTITUMOR ACTIVITY OF MYCOPHENOLIC ACID
The Journal of Antibiotics, 1969 Mycophenolic acid shows significant antitumor activity against several strains of transplantable mouse tumors, some of which were originally established as syngeneic in tumor-host realtionship. Mycophenolic acid was more effective against solid than ascitic tumors. Oral, subcutaneous or intraperitoneal administration was equally effective.
Kunio Ando +4 more
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IMP-dehydrogenase inhibition in human lymphocytes and lymphoblasts by mycophenolic acid and mycophenolic acid glucuronide [PDF]
Clinical Chemistry, 1997 AbstractInosine 5′-monophosphate dehydrogenase (IMP-DH) activities were measured in human lymphocytes (exhibiting type I IMP-DH activity) and human lymphoblasts (exhibiting type II IMP-DH activity) in the presence of various amounts of mycophenolic acid (MPA) (0–20 μmol/L) and MPA glucuronide (MPAG) (0–200 μmol/L).
Andrea Griesmacher +3 more
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Inhibition of nucleotide biosynthesis potentiates the antifungal activity of amphotericin B. [PDF]
PLoS ONE, 2014 The polyene antifungal agent Amphotericin B exhibits potent and broad spectrum fungicidal activity. However, high nephrotoxicity can hinder its administration in resource poor settings.
Dithi Banerjee +2 more
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The inhibition of nucleic acid synthesis by mycophenolic acid [PDF]
Biochemical Journal, 1969 1. Mycophenolic acid, an antibiotic of some antiquity that more recently has been found to have marked activity against a range of tumours in mice and rats, strongly inhibits DNA synthesis in the L strain of fibroblasts in vitro. 2. The extent of the inhibition of DNA synthesis is markedly increased by preincubation of the cells with mycophenolic acid ...
Jennifer M. Cook, T. J. Franklin
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