Results 41 to 50 of about 24,385 (265)

Mycotoxicological monitoring. Part 3. Feedstuffs from raw grain processing

Ветеринария сегодня, 2020
The paper presents the results of mycotoxicological testing of the production batches of sunflower cake and meal, feedstuffs of soybean and wheat bran processing received from domestic processing establishments and livestock farms from 2009 to 2019 ...
G. P. Kononenko, A. A. Burkin, Ye. V. Zotova   +2 more
doaj   +1 more source

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, EarlyView.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +2 more sources

Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]

, 2005
In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Spöhrer, Ute, Vogeser, Michael
core   +1 more source

Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells. [PDF]

, 2014
BACKGROUND: The importance of the genetic background of cancer cells for the individual susceptibility to cancer treatments is increasingly apparent.
Arozarena, Imanol, Erice, O., Ferguson, J., Goicoechea, I., Margison, G.P., Wellbrock, C.   +5 more
core   +5 more sources

Association between mycophenolic acid treatment and infection with specific strains of Pneumocystis jirovecii in solid organ transplant recipients in France and Switzerland: a multicentre, retrospective, cross-sectional study

The Lancet Microbe
Summary: Background: Pneumocystis pneumonia (PCP) case clusters involving solid organ transplant (SOT) recipients have been reported worldwide. Mycophenolic acid, an immunosuppressant used to prevent rejection in SOT recipients that targets the inosine ...
Claire V Hoffmann, PhD, ProfPhD Yannick Le Meur, PhD, Marie-Christine Moal, MD, Anne Grall-Jézéquel, MD, Nathan Le Nan, ProfPhD Nicolas Papon, ProfPhD Gilles Nevez, Solène Le Gal, PhD, Anne Totet, Hakim Mazouz, Jean-Philippe Bouchara, Virginie Besson, Emeline Scherer, Didier Ducloux, Konrad Mühlethaler, Pierre L Bonnet, Julie Bonhomme, Thierry Lobbedez, Valérie Chatelet, Céline Nourrisson, Cyril Garrouste, Françoise Botterel, Marie Matignon, Frederic Dalle, Claire Tinel, Danièle Maubon, Johan Noble, Boualem Sendid, Jordan Leroy, François Provot, Marie-Fleur Durieux, Clément Danthu, Jean Menotti, François Bailly, Christophe Ravel, Moglie Le Quintrec, Anne Debourgogne, Marc Ladriere, Florent Morio, Magali Giral, Lilia Hasseine, Laetitia Albano, Nicolas Argy, Richard Dorent, Arnaud Fekkar, Valérie Pourcher, Estelle Cateau, Antoine Thierry, Antoine Huguenin, Alain Wynckel, Florence Robert-Gangneux, Elsa Vabret, Damien Costa, Dominique Bertrand, Pierre Flori, Emmanuelle Tavernier, Julie Brunet, Laura Braun, Xavier Iriart, Arnaud Del Bello, Guillaume Desoubeaux, Matthias Buchler, Natalja Kulagina, Vincent Courdavault   +63 more
doaj   +1 more source

Mycophenolic Acid in Silage [PDF]

Applied and Environmental Microbiology, 2000
ABSTRACT We examined 233 silage samples and found that molds were present in 206 samples with counts between 1 × 10 3 and 8.9 × 10 7 (mean, 4.7 × 10 6 ) CFU/g. Mycophenolic acid, a metabolite of Penicillium roqueforti , was detected by
I, Schneweis, K, Meyer, S, Hörmansdorfer, J, Bauer   +3 more
openaire   +2 more sources

Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3. [PDF]

, 1991
The T cell antigen receptor consists of the Ti alpha/beta heterodimer which recognizes antigen, and the associated CD3 chains, thought to be involved in signal transduction.
Tan, L, Turner, J, Weiss, A
core   +1 more source

A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels

Communications Biology, 2021
Guste Urbonaite and Jimmy Tsz Hang Lee et al. present a droplet-based single-cell sequencing method optimized for use in yeast. They use their method—yeastDropSeq—to investigate the changes in gene expression profiles following treatment with the ...
Guste Urbonaite, Jimmy Tsz Hang Lee, Ping Liu, Guillermo E. Parada, Martin Hemberg, Murat Acar   +5 more
doaj   +1 more source

Compartmentalized biosynthesis of mycophenolic acid [PDF]

Proceedings of the National Academy of Sciences, 2019
Significance Here, we elucidate the full biosynthetic pathway of the fungal natural product mycophenolic acid (MPA). Besides the intriguing enzymatic mechanisms, we reveal that the MPA biosynthetic enzymes are elegantly compartmentalized; the oxygenase MpaB′ is the long-sought enzyme responsible for initiating the oxidative cleavage ...
Wei Zhang, Lei Du, Zepeng Qu, Xingwang Zhang, Fengwei Li, Zhong Li, Feifei Qi, Xiao Wang, Yuanyuan Jiang, Ping Men, Jingran Sun, Shaona Cao, Ce Geng, Fengxia Qi, Xiaobo Wan, Changning Liu, Shengying Li   +16 more
openaire   +2 more sources

In vitro activity of immunosuppressive drugs against Plasmodium falciparum [PDF]

, 2014
Background Solid organ transplant recipients are particularly vulnerable for infectious diseases due to prolonged immunosuppressive treatment. Residents of endemic regions and travellers may be exposed to malaria and may, therefore, require prolonged ...
Felix Loetsch, Heinz Burgmann, Khalid Rehman, Luzia Veletzky, Michael Ramharter, Tilman Lingscheid, Wolfgang Poeppl   +6 more
core   +2 more sources