Results 51 to 60 of about 24,385 (265)
Kidney Transplantation for Erdheim-Chester Disease
Erdheim-Chester disease is a rare inflammatory disease that infiltrates skeletal and extra-skeletal tissue. Chronic kidney disease (CKD) in Erdheim-Chester disease is usually attributed to retroperitoneal lesions that lead to urologic obstruction and ...
Jongwon Yoo +8 more
doaj +1 more source
Mycotoxicological monitoring. Part 1. Complete mixed feed for pigs and poultry (2009–2018)
Results of the ten-year annual mycotoxicological testing of complete mixed feeds for pigs and poultry submitted by holdings and processing establishments located in the Northwestern, Central, Southern, Volga and Ural Federal Districts are presented ...
G. P. Kononenko +2 more
doaj +1 more source
Multinational evaluation of mycophenolic acid, tacrolimus, cyclosporin, sirolimus, and everolimus utilization [PDF]
Background: Increasing immunosuppressant utilization and expenditure is a worldwide challenge as more people successfully live with transplanted organs.
Gardiner, Kyle M. +2 more
core +1 more source
Mycophenolic acid (MPA, 1) and its derivatives are first-line immunosuppressants used in organ transplantation and for treating autoimmune diseases. Despite chemical synthetic achievements, the biosynthetic formation of a seven-carbon carboxylic acid ...
Xiwei Chen +6 more
doaj +1 more source
Mycophenolic acid (MPA) is the active ingredient in the most important immunosuppressive pharmaceuticals. It has antifungal, antibacterial, antiviral, anti-psoriasis, and antitumor activities.
Hala A. Ammar +3 more
doaj +1 more source
First-principles molecular structure search with a genetic algorithm
The identification of low-energy conformers for a given molecule is a fundamental problem in computational chemistry and cheminformatics. We assess here a conformer search that employs a genetic algorithm for sampling the low-energy segment of the ...
Baldauf, Carsten +2 more
core +2 more sources
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source
Inhibition of nucleotide biosynthesis potentiates the antifungal activity of amphotericin B. [PDF]
The polyene antifungal agent Amphotericin B exhibits potent and broad spectrum fungicidal activity. However, high nephrotoxicity can hinder its administration in resource poor settings.
Dithi Banerjee +2 more
doaj +1 more source
Pharmacokinetic Variability of Mycophenolic Acid in Pediatric and Adult Patients with Hematopoietic Stem Cell Transplantation [PDF]
The aim of this study was to evaluate the pharmacokinetic variations of mycophenolic acid (MPA), the active metabolite of mycophenolate mofetil (MMF), in both pediatric and adult patients following hematopoietic stem cell transplantation (HSCT).
Chow, Diana S-L. +2 more
core +1 more source
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source

