Results 21 to 30 of about 6,134 (178)

Prevalence of Urogenital Mycoplasmas Among Men with NGU in Upper Silesia, Poland. Preliminary Study [PDF]

Polish Journal of Microbiology, 2016
The prevalence of urogenital mycoplasmas in men with NGU in Upper Silesia (Poland) was studied. Mycoplasmas were detected in 36.7% men (Ureaplasma parvum and Mycoplasma genitalium were found in 30% and 16.7% respectively). Urealyticum urealyticum was not
Alicja Ekiel, Małgorzata Aptekorz, Piotr Kłuciński, Dominika Smolec, Barbara Wiechuła, Jarosław Jóźwiak, Gayane Martirosian   +6 more
doaj   +1 more source

Mycoplasma genitalium infection in the female reproductive system: Diseases and treatment

Frontiers in Microbiology, 2023
Mycoplasma genitalium is a newly emerged sexually transmitted disease pathogen and an independent risk factor for female cervicitis and pelvic inflammatory disease. The clinical symptoms caused by M. genitalium infection are mild and easily ignored.
Jianwei Yu, Yan Zhou, Haodang Luo, Xiaoling Su, Tian Gan, Jingyun Wang, Zufeng Ye, Zhongliang Deng, Jun He, Jun He   +9 more
doaj   +1 more source

Prevalence of cervical colonization by Ureaplasma parvum, Ureaplasma urealyticum, Mycoplasma hominis and Mycoplasma genitalium in childbearing age women by a commercially available multiplex real-time PCR: An Italian observational multicentre study

Journal of Microbiology, Immunology and Infection, 2018
Background: Mycoplasmas are frequently isolated from the genital tract. New molecular PCR-based methods for the detection of mycoplasmas can better define the real epidemiology of these microorganisms. The aim of this study was to evaluate the prevalence
Christian Leli, Antonella Mencacci, Maria Agnese Latino, Pierangelo Clerici, Mario Rassu, Stefano Perito, Roberto Castronari, Eleonora Pistoni, Eugenio Luciano, Daniela De Maria, Cristina Morazzoni, Michela Pascarella, Silvia Bozza, Alessandra Sensini   +13 more
doaj   +1 more source

Detection of macrolide and fluoroquinolone resistance-associated 23S rRNA and parC mutations in Mycoplasma genitalium by nested real-time PCR

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundTraditional drug susceptibility testing cannot be performed in clinical laboratories due to the slow-growing characteristics of Mycoplasma genitalium when cultured in vitro. Sanger sequencing is the standard method for detecting drug resistance-
Wenyin He, Ying Yuan, Junyu Liang, Xuejiao Fan, Lei Li, Xingfei Pan   +5 more
doaj   +1 more source

Yeast Knockout Strain Collection: Driving Functional Genomics, Biotechnological Applications and Human Disease Research

Yeast, EarlyView.
ABSTRACT The knockout strain collection of Saccharomyces cerevisiae has served as a valuable resource for functional genomics and yeast‐based biotechnology studies. A comprehensive single‐gene knockout strain collection, covering nearly all non‐essential genes, together with complementary mutant collections for essential genes, including temperature ...
Takashi Hirasawa
wiley   +1 more source

Virtual cell construction for artificial intelligence‐driven drug discovery

British Journal of Pharmacology, EarlyView.
Cells are the fundamental units through which genetic variation and pharmacological perturbations influence disease processes and therapeutic responses. However, cellular responses to intervention are strongly shaped by biological context, creating a central challenge for drug discovery: predicting how specific perturbations reshape cellular systems ...
Yuran Jia, Xiao Xing, Haoyang Han, Yuansong Zhao, Shiyao Zhou, Jingjing Chen   +5 more
wiley   +1 more source

Drug Resistance–Associated Mutations in Mycoplasma genitalium in Female Sex Workers, Japan

Emerging Infectious Diseases, 2015
Mycoplasma genitalium was detected in 21 (14.1%) of 149 vaginal swab samples and in 1 (0.7%) of 149 throat washing samples from female sex workers during 2013–2014 in Japan. Prevalences of M.
Takashi Deguchi, Mitsuru Yasuda, Kengo Horie, Kensaku Seike, Mina Kikuchi, Kohsuke Mizutani, Tomohiro Tsuchiya, Shigeaki Yokoi, Masahiro Nakano, Shinji Hoshina   +9 more
doaj   +1 more source

Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium

Emerging Infectious Diseases, 2020
Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium.
Duygu Durukan, Michelle Doyle, Gerald Murray, Kaveesha Bodiyabadu, Lenka Vodstrcil, Eric P.F. Chow, Jorgen S. Jensen, Christopher K. Fairley, Ivette Aguirre, Catriona S. Bradshaw   +9 more
doaj   +1 more source

Sexually Transmitted Infection Prevalence and Determinants Among Sexual Health Clinic Attendees in Bucharest, Romania

International Journal of Dermatology, EarlyView.
Cross‐sectional study among 70 sexual health clinic attendees (70% MSM) in Bucharest combining multisite STI testing with knowledge, attitudes, and practices assessment. Key findings include 35.5% bacterial STI prevalence, essential extragenital testing, and cost barriers to screening uptake.
Andrei Tanasov, George‐Sorin Tiplica
wiley   +1 more source

Methodology of the French National Study “Context of Sexualities in France” (CSF‐2023)

Perspectives on Sexual and Reproductive Health, EarlyView.
ABSTRACT Introduction The 2023 national survey “Context of Sexualities in France” (CSF‐2023) explores sexuality and sexual health in France. Methods Conducted between November 2022 and December 2023, CSF‐2023 is a cross‐sectional probability survey involving 21,259 respondents aged 15–89 in continental France.
Caroline Moreau, Aline Bohet, Armelle Andro, Yann Le Strat, Nathalie Bajos   +4 more
wiley   +1 more source