Results 61 to 70 of about 904,551 (309)

Risk factors for postcalving intramammary infection with Mycoplasma species in first-lactation cows on a conventional dairy farm: A retrospective case control study

JDS Communications
Mycoplasma spp. are highly contagious bacteria that cause chronic, subclinical infections in dairy cattle and are intrinsically resistant to many antimicrobials.
Alejandra Zapata-Salazar, Matthias Wieland, Francisco A. Leal Yepes   +2 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Chronic osteomyelitis with pathological fracture induced by Mycoplasma hominis infection: a case report and review of the literature

Frontiers in Medicine
Mycoplasma hominis, commonly residing in the genitourinary tract, can cause rare extragenital infections, especially in immunocompromised individuals. This report details a case of chronic osteomyelitis with a pathological femur fracture in a 79-year-old
Ling-Na Zhu, Wen-Bin Shen, Xiao-Yan Zou, Jiang-Cheng Zuo, Ning Xiao   +4 more
doaj   +1 more source

The role of mixed Mycoplasma and Herpesvirus infections in case of skin lesions in children

Детские инфекции (Москва), 2019
Numerous literature data show the role of mycoplasma infection in the development of non-respiratory lesions of various organs and systems, including the skin.
H. O. Kuvardina, F. S. Kharlamova, I. V. Polesko, O. V. Shamsheva, O. S. Ostapuschenko   +4 more
doaj   +1 more source

Mycoplasma genitalium infections can comprise a mixture of both fluoroquinolone-susceptible and fluoroquinolone-resistant strains

, 2021
BACKGROUND: Mycoplasma genitalium was recently added to the CDC's antimicrobial resistance threats 'watch list', as it has rapidly become resistant to mainstay treatments.
Bletchly, Cheryl, Lowry, Kym, Whiley, David M, Nimmo, Graeme R, Sweeney, Emma L   +4 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Prospective serological and molecular cross-sectional study focusing on Bartonella and other blood-borne organisms in cats from Catalonia (Spain)

Parasites & Vectors, 2022
Background There is limited clinical or epidemiological knowledge regarding Bartonella infection in cats, and no serological studies have compared the presence of antibodies against different Bartonella species.
Alejandra Álvarez-Fernández, Ricardo Maggi, Gerard Eduard Martín-Valls, Marta Baxarias, Edward Bealmear Breitschwerdt, Laia Solano-Gallego   +5 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Pneumonia Unveiled A Comprehensive Exploration of Causes, Symptoms, and Prevention

Journal of Pharmaceutical Research
A major contributor to atypical community-acquired pneumonia, Mycoplasma pneumoniae poses a special challenge in the clinical and scientific arenas because of its unique features, which include its tiny genome size, absence of a cell wall, and ...
Rashmi Wani, Sunny Roy, Darsh Jain, Shreya Menon   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source