Results 111 to 120 of about 13,458 (304)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Canine mycoplasmas [PDF]

open access: yes, 2019
Mikoplazme su najjednostavniji i najmanji prokariotski organizmi koji se mogu samostalno razmnožavati. Izdvojene su iz svih vrsta domaćih životinja, mnogih vrsta divljih životinja, ptica, ljudi, insekata, biljaka i gmazova. Raširene su po cijelom svijetu
Galović, Mihael   +2 more
core   +1 more source

Mycoplasmas: what is the role in human infections? [PDF]

open access: yes, 2005
Mycoplasmas, the common denomination of the Mycoplasma and Ureaplasma genera, represent a unique and complex group of microorganisms that has been ignored by the majority of diagnostic laboratories, not only because of its fastidious growth, absence of ...
Exposto, Filomena   +3 more
core  

Mycoplasmas: Sophisticated, Reemerging, and Burdened by Their Notoriety

open access: yes, 1997
Mycoplasmas are most unusual self-replicating bacteria, possessing very small genomes, lacking cell wall components, requiring cholesterol for membrane function and growth, using UGA codon for tryptophan, passing through "bacterial-retaining" filters ...
Joel B. Baseman, Joseph G. Tully
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Pathogens Associated with Bovine Mastitis: The Experience of Bosnia and Herzegovina

open access: yesVeterinary Sciences
To obtain improved insights into the complex microbial aetiology of bovine mastitis, this study investigated the pathogens involved in cattle mastitis in Bosnia and Herzegovina.
Maid Rifatbegović   +4 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Development of human mycoplasma vaccines: navigating the IL-17A paradox

open access: yesFrontiers in Immunology
Despite decades of effort, effective vaccines against pathogenic human mycoplasmas remain elusive, largely due to vaccine-enhanced disease (VED).
Wenjun Zhang, Tingting Li, Fangyi Guo
doaj   +1 more source

The gram stain smear: A screening test for genital mycoplasmas from vaginal specimens prior to culture.

open access: yes, 2004
Result of 168 vaginal specimens from women examined for genital mycoplasmas showed that more of these organisms were isolated from specimens whose Gram stain smears were devoid of Gram positive bacilli (GPB) (43%) as against those whose smears contain ...
NR Okwoli   +5 more
core   +1 more source

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