Results 41 to 50 of about 13,458 (304)
Frontiers in MicrobiologyBackgroundAntimicrobial resistance in Mycoplasma gallisepticum (MG) poses a significant threat to global poultry production, as traditional antibiotics, particularly macrolides, are becoming increasingly ineffective due to growing resistance.
Sabrina Zidi +11 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Genes involved in translation of Mycoplasma hyopneumoniae and Mycoplasma synoviae
Genetics and Molecular Biology, 2007 This is a report on the analysis of genes involved in translation of the complete genomes of Mycoplasma hyopneumoniae strain J and 7448 and Mycoplasma synoviae.
Mônica de Oliveira Santos +3 more
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Common Swine Mycoplasmas [PDF]
, 2014 Mycoplasmas are the smallest organisms (200-300nm) that are capable of growth in cell free medium. They are different from bacteria in that they have no cell walls but are bounded by a unite membrane.
Kennedy, Sally +2 more
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Mycoplasmas & Mycobacteria: Minimalists at Work [PDF]
, 2014 Mycoplasmas and mycobacteria are two types of opportunistic pathogens whose prevalence and virulence have long been underestimated. As a broad overview, this paper will explore the current understanding of these bacteria as well as some common ...
Killpack, Shalee
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Decoding Mycoplasma Nucleases: Biological Functions and Pathogenesis
ToxinsNucleases are critical metabolic enzymes expressed by mycoplasmas to acquire nucleic acid precursors from the host for their parasitic existence. Certain nucleases, either membrane-bound or secreted, not only contribute to the growth of mycoplasmas but ...
Xinchao Yi +10 more
doaj +1 more source
The persistence of mycoplasmas in the urogenital tract of men in the Antarctic
, 1974 A series of meatal swabs, taken from 17 men over a period of 17 months during their tour at an Antarctic base was examined for mycoplasmas. The number of organisms isolated never exceeded 104 and not every specimen from each man yielded mycoplasmas ...
Holmes, M.J. +5 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source