Results 31 to 40 of about 39,492 (194)

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source

Defensive medicine in dermatological practice – Dermatopathology as a mirror of structural challenges

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Defensive medicine refers to diagnostic or therapeutic actions taken primarily to reduce legal liability rather than to benefit the patient. In dermatopathology, defensive practices manifest in frequent immunohistochemical testing, overly cautious report phrasing, and reliance on multidisciplinary tumor boards.
Cornelia Sigrid Lissi Müller   +2 more
wiley   +1 more source

Temporohyoid osteoarthropathy presenting as unilateral epistaxis in a mare

open access: yesEquine Veterinary Education, EarlyView.
Summary An 18‐year‐old Selle Français mare presented with recurrent mild left‐sided epistaxis. Guttural pouch endoscopy revealed multiple focal mucosal erosions and congested vasculature overlying an enlarged left temporohyoid joint (THJ), and standing cone beam computed tomography (CBCT) confirmed moderate left‐sided temporohyoid osteoarthropathy (THO)
S. E. Sage   +4 more
wiley   +1 more source

Evaluation of the Diagnostic Accuracy of the Quantitative Point‐of‐Care SD Biosensor Standard G6PD Test for Assessment of G6PD Deficiency in Infectious Diseases

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.
Flavia Regina Medeiros da Silva   +7 more
wiley   +1 more source

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu   +13 more
wiley   +1 more source

Dermatology 2.0: Precision medicine for inflammatory skin diseases

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Digital immune mapping of transcriptomics profiles from inflammatory skin disease biopsies enables precise molecular diagnosis, quantification of immune modules and personalized therapy selection by matching dominant immune signatures to targeted treatments.
Jeremy Di Domizio   +4 more
wiley   +1 more source

Epidemiology of Salmonid Rickettsial Septicemia (SRS) in Farmed Salmon: The Role of Sea Lice Infestations in Mortality Risk

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Piscirickettsia salmonis , the causal agent of salmonid rickettsial septicemia (SRS), is the main pathogen affecting farmed salmonids in Chile. Outbreaks of SRS lead to substantial economic losses for producers. Many determinants related to SRS outcomes are still poorly understood.
Benjamín Diethelm‐Varela   +7 more
wiley   +1 more source

Pediatric Papular Mycosis Fungoides Treated With Phototherapy: A Case Series

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Papular mycosis fungoides (PMF) is a rare clinical variant with limited data on long‐term outcomes, particularly in children. Our study describes sociodemographic, clinical, therapeutic, and follow‐up data in 5 pediatric patients with PMF, all treated with phototherapy (PUVA, PUVAsol or narrowband UVB).
Mariana de la Vega   +3 more
wiley   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

open access: yesPhotochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal   +3 more
wiley   +1 more source

Apoptosis kinetics of purified and PBMC‐associated lymphocytes after photopheresis‐like 8‐methoxypsolaren/UVA treatment

open access: yesPhotochemistry and Photobiology, EarlyView.
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde   +6 more
wiley   +1 more source

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