Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
Evidence for down-regulation of beta-2-adreno-ceptors in cirrhotic patients with severe ascites [PDF]
The density and affinity of beta-2-adrenoceptors on mononuclear cells from peripheral blood were studied in fifteen patients with cirrhosis of different severity and in thirteen controls. There was no significant difference between cirrhotic patients and
AlexanderL. Gerbes +22 more
core +1 more source
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma. [PDF]
Paraneoplastic myelitis is a rare inflammatory disorder most frequently associated with solid tumors or lymphoproliferative disorders. Patients often harbor onconeuronal antibodies and their prognosis is usually poor.
Bataller, L. +9 more
core +1 more source
Sarcoidosis Presenting as Longitudinally Extensive Transverse Myelitis: A Case Report
Spinal cord sarcoidosis is a rare condition that can present as a longitudinally extensive transverse myelitis. Current imaging may suggest this pathology, but the final diagnosis relies on the histologic findings.
Joudia Touri +2 more
doaj +1 more source
Pediatric multiple sclerosis: update on diagnostic criteria, imaging, histopathology and treatment choices [PDF]
Pediatric multiple sclerosis (MS) represents less than 5% of the MS population, but patients with pediatric-onset disease reach permanent disability at a younger age than adult onset patients.
A Ghezzi +112 more
core +2 more sources
Entzündliche Erkrankungen der Wirbelsäule und des Myelons [PDF]
Zusammenfassung: Entzündliche Erkrankungen der Wirbelsäule und des Myelons haben vielfältige Ursachen. Mit Ausnahme der degenerativ bedingten entzündlichen Veränderungen der Wirbelsäule selbst sind bakteriell, viral oder autoimmun vermittelte ...
Ahlhelm, F.J. +5 more
core
MOG encephalomyelitis: international recommendations on diagnosis and antibody testing [PDF]
Over the past few years, new-generation cell-based assays have demonstrated a robust association of autoantibodies to full-length human myelin oligodendrocyte glycoprotein (MOG-IgG) with (mostly recurrent) optic neuritis, myelitis and brainstem ...
Aktas, O. +18 more
core +9 more sources
Review Article : Neuromuscular causes of weakness in critically ill patients [PDF]
Multiple predisposing factors are responsible for the development of neuromuscular weakness in a critically ill patient. Thorough history and physical examination is paramount and should not be omitted despite that the majority of patients are ...
Govindarajan, Raghav, Katyal, Nakul
core +1 more source

