Results 61 to 70 of about 75,070 (238)

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

MOG antibody-associated disease – a new entity or one of the forms of the NMO spectrum?

Aktualności Neurologiczne, 2019
Myelin oligodendrocyte glycoprotein (MOG) is a protein involved in the maintenance of the myelin structure. Recent studies have shown that serum anti-MOG antibodies are found in some of the patients who meet the diagnostic criteria for neuromyelitis ...
Dominika Czarnecka, Mariusz Stasiołek
doaj   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Transverse Myelitis in a Rural Australian Emergency Department: Case Report [PDF]

Acute transverse myelitis (ATM) is a rare neurologic condition with rapid onset of weakness, sensory changes, and occasional bowel or bladder symptoms. This case report will explore a male patient presenting with symptoms consistent with ATM to a rural ...
Hulsbos, Nadia, Levick, Jessica, Copeman, Mitchell   +2 more
core   +1 more source

Systemic Lupus Erythematosus and Acute Transverse Myelitis: An Unusual Association—A Case Report

Case Reports in Medicine
Acute transverse myelitis is a rare neurological complication of systemic lupus erythematosus (SLE), particularly in sub-Saharan African origin patients. We report a case of acute transverse myelitis in a sub-Saharan African origin patient with SLE. This
Baowêndsôm Armelle Djamilatou Sawadogo, Yannick Laurent Tchenadoyo Bayala, Ahmed Devis Wendyam Zougmoré, Marcellin Bonkoungou, Fulgence Kaboré, Wendlassida Joëlle Stéphanie Zabsonré/Tiendrébéogo, Dieu-Donné Ouédraogo   +6 more
doaj   +1 more source

Efficacy of Fampridine on Refractory Optic Neuritis in Neuromyelitis Optica Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) usually occur with acute refractory optic neuritis (ON). However, there is a lack of efficacious treatments to improve recovery. Since fampridine has been found to improve the prognosis of multiple sclerosis (MS) and MS‐related ON, it is necessary to explore the efficacy of fampridine ...
Hongxuan Wang, Wanru Chen, Xiangpen Li, Hengjian Lu, Chenguang Li, Xiaoni Zhang, Lulu Bu, Xiaoyu Xu, Qingyu Shen, Ying Peng   +9 more
wiley   +1 more source

Lumbar decompression and fusion for symptomatic spinal stenosis in a patient with chronic thoracic sensory level from prior transverse myelitis: a case report

Journal of Medical Case Reports
Background Many patients with transverse myelitis suffer from sensory loss below the spinal level of the lesion. This is commonly associated with chronic neuropathic pain.
Benjamin D. Pesante, Mitch R. Paro, Tooba Nadeem, Ketan R. Bulsara, David B. Choi   +4 more
doaj   +1 more source

Cerebrospinal fluid lactate in dogs with inflammatory central nervous system disorders

Journal of Veterinary Internal Medicine, 2019
Background Cerebrospinal fluid (CSF) lactate is frequently used as a biomarker in humans with inflammatory central nervous system (CNS) disorders including bacterial meningitis and autoimmune disorders such as multiple sclerosis. Hypothesis Cerebrospinal
Christopher L. Mariani, Carolyn J. Nye, Debra A. Tokarz, Lauren Green, Jeanie Lau, Natalia Zidan, Peter J. Early, Julien Guevar, Karen R. Muñana, Natasha J. Olby, Sarita Miles   +10 more
doaj   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Case report: Hypereosinophilic atopic transverse myelitis

, 2018
Atopic transverse myelitis is a rare disorder that is defined as a localized myelitis of an unknown cause in patients with either high immunoglobulin E (IgE) level or mite‑specific IgE or coexistent atopic disease.
Aworanti, O.W., Fasola, F.A.
core   +1 more source