Results 81 to 90 of about 75,070 (238)

Top‐Down CSF Peptidomics Reveals Disease‐Associated Peptide Signatures and Oxidative Modifications in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Multiple sclerosis and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory demyelinating diseases of the CNS whose diagnosis is mainly based on clinical evidence, magnetic resonance imaging, and the analysis of cerebrospinal fluid (CSF). Current approaches provide only partial insight into disease‐related biological processes, thus
Cristina Contini   +9 more
wiley   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

open access: yesBrain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu   +11 more
wiley   +1 more source

Getting Transverse Myelitis

open access: yes, 2014
This blog post focuses on Slayton\u27s own experience with having Transverse ...
Slayton, Robert A.
core   +1 more source

Spinal Cord Involvement in MS and Other Demyelinating Diseases

open access: yesBiomedicines, 2020
Diagnostic accuracy is poor in demyelinating myelopathies, and therefore a challenge for neurologists in daily practice, mainly because of the multiple underlying pathophysiologic mechanisms involved in each subtype.
Mariano Marrodan   +2 more
doaj   +1 more source

A novel myopathy with autophagic vacuoles associated with biallelic variants in CLN8

open access: yesBrain Pathology, EarlyView.
We describe a novel adult‐onset myopathy with autophagic vacuoles and characteristic features of ceroid lipofuscinosis associated with biallelic CLN8 variants, seizures, and muscle weakness. Autophagosomal/lysosomal deposition of curvilinear, autofluorescent material containing the mitochondrial adenosine triphosphate (ATP) synthase membrane subunit c ...
Ulrika Lindgren   +5 more
wiley   +1 more source

Clinical and cerebrospinal fluid (CSF) profile and CSF criteria for the diagnosis of spinal cord schistosomiasis Aspectos clínicos e liquóricos e critérios para o diagnóstico liquórico de esquistossomose medular

open access: yesArquivos de Neuro-Psiquiatria, 2003
OBJECTIVES: To describe the clinical and CSF findings among patients with presumptive neuroschistosomiasis (NS) and to suggest a classification for the CSF diagnosis of presumptive NS.
Otávio Augusto Moreno-Carvalho   +6 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu   +5 more
wiley   +1 more source

Autoimmune GFAP astrocytopathy with eosinophils on cerebrospinal fluid cytology and isolated spinal cord lesions on MRI: a case report

open access: yesFrontiers in Immunology
BackgroundAutoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an autoimmune inflammatory disorder of the central nervous system associated with GFAP-IgG.
Dongdong Zhang   +4 more
doaj   +1 more source

Complete surgical excision of a type V‐variant dermoid sinus (V/VI overlap) associated with spina bifida in a Shiba Inu dog: A case report

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To describe the clinical, imaging, surgical, and histopathologic features of a type V/VI overlap dermoid sinus (DS), and highlight diagnostic and therapeutic considerations. Study design Case report. Animal A 16‐month‐old spayed female Shiba Inu dog.
Ji‐Eun Jeong   +2 more
wiley   +1 more source

Cervical Osteomyelitis with Thoracic Myelitis and Meningitis in a Diabetic Patient

open access: yes, 2015
A 45-year-old man with a history of untreated diabetes mellitus had a persisting fever, back pain, and diarrhea. The primary care physician diagnosed the patient with the flu and gastroenteritis.
Koichi Iwatsuki   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy