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Myelodysplastic syndromes

HemaSphere, 2019
Johanna Ungerstedt, (Coordinating Author)
doaj   +3 more sources

Myelodysplastic syndromes and autoimmune phenomena – case report and literature overview [PDF]

Liječnički vjesnik, 2023
Myelodysplastic syndromes are a heterogeneous group of hematopoiesis disorders, characterized by dysplastic changes in one or more hematopoietic lineages, ineffective hematopoiesis, and peripheral blood cytopenias.
Ana Zelić Kerep, Ana Kotris, Marino Narančić, Inga Mandac Smoljanović   +3 more
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Experiences and Support Needs of Caregivers of Patients with Higher-Risk Myelodysplastic Syndrome via Online Bulletin Board in the USA, Canada and UK

Oncology and Therapy, 2023
Introduction Patients with higher-risk myelodysplastic syndromes (MDS) face considerable challenges in disease management and often require caregiver support.
Pauline Frank, Anne Olshan, Tracey Iraca, Cindy Anthony, Sophie Wintrich, Emma Sasse   +5 more
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Whole exome sequencing reveals a novel LRBA mutation and clonal hematopoiesis in a common variable immunodeficiency patient presented with hemophagocytic lymphohistiocytosis

Experimental Hematology & Oncology, 2021
Common variable immunodeficiency (CVID) was a kind of primary immunodeficiency disorders with heterogeneous phenotype and genotype. Lipopolysaccharide-responsive and beige-like anchor (LRBA) mutation was identified as disease associated in CVID, advanced
Yanling Ren, Feng Xiao, Fei Cheng, Xin Huang, Jianhu Li, Xiaogang Wang, Wei Lang, Xinping Zhou, Jianping Lan, Hongyan Tong   +9 more
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Myelodysplastic syndromes

HemaSphere, 2018
Eva Hellström Lindberg
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The myelodysplastic syndromes [PDF]

Blood Reviews, 1987
The myelodysplastic syndromes constitute a fascinating model for monoclonal premalignant disorders. Haemopoiesis is 'dysplastic' with inefficient maturation of a slowly expanding or sometimes of a stable population, of blood cell precursors. About one third of the patients evolve into acute leukaemia, the result of either a progressive expansion of the
M.A. Boogaerts, R.L. Verwilghen
openaire   +6 more sources

Myelodysplastic syndromes [PDF]

Seminars in Diagnostic Pathology, 2011
Myelodysplastic syndromes (MDS) are hematopoietic neoplasms characterized by an ineffective hematopoiesis associated with cytopenia(s), functional abnormalities of bone marrow lineages, morphologic dysplasia, and a progression to acute myeloid leukemia.
Jiehao, Zhou, Attilio, Orazi, Magdalena B, Czader   +2 more
openaire   +4 more sources

The high NRF2 expression confers chemotherapy resistance partly through up-regulated DUSP1 in myelodysplastic syndromes

Haematologica, 2019
Although cytarabine has been widely considered as one of the chemotherapy drugs for high-risk myelodysplastic syndromes (MDS), the overall response rate is only approximately 20-30%.
Peipei Lin, Yanling Ren, Xiaomei Yan, Yingwan Luo, Hua Zhang, Meenu Kesarwani, Jiachen Bu, Di Zhan, Yile Zhou, Yuting Tang, Shuanghong Zhu, Weilai Xu, Xinping Zhou, Chen Mei, Liya Ma, Li Ye, Chao Hu, Mohammad Azam, Wei Ding, Jie Jin, Gang Huang, Hongyan Tong   +21 more
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IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis

Haematologica, 2010
Background Myelodysplastic syndromes are a heterogeneous group of hematopoietic stem cell disorders with a high propensity to transform into acute myeloid leukemia.
Felicitas Thol, Eva M. Weissinger, Jürgen Krauter, Katharina Wagner, Frederik Damm, Martin Wichmann, Gudrun Göhring, Christiane Schumann, Gesine Bug, Oliver Ottmann, Wolf-Karsten Hofmann, Brigitte Schlegelberger, Arnold Ganser, Michael Heuser   +13 more
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Activation of cytotoxic T-cell receptor γδ T lymphocytes in response to specific stimulation in myelodysplastic syndromes

Haematologica, 2008
Background We previously reported that the function and proliferation of natural killer cells in myelodysplastic syndromes are defective. T-cell receptor γδ T cells are other important components of innate immunity that have been recently implicated in ...
Jean-Jacques Kiladjian, Géraldine Visentin, Emilie Viey, Sylvie Chevret, Virginie Eclache, Jerome Stirnemann, Jean Henri Bourhis, Salem Chouaib, Pierre Fenaux, Anne Caignard   +9 more
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