Results 191 to 200 of about 2,285,924 (374)
ABSTRACT B‐cell maturation antigen (BCMA)‐directed chimeric antigen receptor (CAR) T‐cell therapies have revolutionized the approach and management of relapsed/refractory multiple myeloma (RRMM), and as of 2025, idecabtagene vicleucel (ide‐cel) and ciltacabtagene autoleucel (cilta‐cel) are the only BCMA‐targeted CAR T‐cell therapies approved by the FDA.
Hector Garcia Pleitez +5 more
wiley +1 more source
Proposals for the classification of the myelodysplastic syndromes
J. Bennett +7 more
semanticscholar +1 more source
ABSTRACT Background Toll‐like receptors (TLRs) play a critical role in innate immunity by recognizing pathogen‐associated and damage‐associated molecular patterns. Genetic polymorphisms in TLR genes can modulate immune responses and have been implicated in the outcomes of allogeneic hematopoietic cell transplantation (HCT).
Takaaki Konuma +10 more
wiley +1 more source
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes.
D. Steensma +6 more
semanticscholar +1 more source
ABSTRACT Acute myeloid leukemia (AML) in elderly patients presents a major therapeutic challenge, as many are deemed unfit for intensive chemotherapy due to age, comorbidities, or frailty. Venetoclax in combination with hypomethylating agents (HMA) has emerged as a standard‐of‐care for this population, yet outcomes remain heterogeneous and predictive ...
Ernesto Vigna +11 more
wiley +1 more source
Biologic characteristics of acute leukemia after myelodysplastic syndrome [PDF]
Masahiro Masuya +8 more
openalex +1 more source
The PNH French Working Group Experience: Building a Strong Network of Cytometrists
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon +9 more
wiley +1 more source
Hematopathology Practice in the Digital Era: What has Changed?
ABSTRACT Hematopathology workflows are complex, since they include numerous data points necessary for guiding further testing, diagnosis, and patient management. The workflows start with complete blood cell counts, with subsequent morphologic evaluation of peripheral blood (PB) and bone marrow (BM).
Olga Pozdnyakova
wiley +1 more source

