Venetoclax Plus Hypomethylating Agents for Treatment-Naïve Myelodysplastic Syndromes with Increased Blasts: A Prospective Multicenter Cohort Study. [PDF]
Zhao N +14 more
europepmc +1 more source
Unilateral Pulmonary Artery Lesion in an Immunocompromised Patient
We report a case of a unilateral septic pulmonary artery thrombus presenting as pulmonary infarction and pulmonary hypertension in an immunocompromised host. ABSTRACT We report a 62‐year‐old man with myelodysplastic syndrome on immunosuppressive therapy who presented with right lung consolidation and neutropenia. Despite broad antimicrobial therapy for
Seunghoon Lee +7 more
wiley +1 more source
Observational and Genetic Association of Myelodysplastic Syndromes (MDS) and Autoimmune Diseases in Adults. [PDF]
Li Q +16 more
europepmc +1 more source
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo +2 more
wiley +1 more source
The patient voice: measuring what matters in lower-risk myelodysplastic syndromes treated with imetelstat. [PDF]
Chien KS, DeZern AE.
europepmc +1 more source
ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni +17 more
wiley +1 more source
Comparative efficacy and safety of pharmacological treatments for lower-risk myelodysplastic syndromes: a Systematic Review and network meta-analysis. [PDF]
Zhang H, Hu J, Jiang Y, Deng L, Liu S.
europepmc +1 more source
ABSTRACT Acute Myeloid Leukemia predominantly affects older adults, who often present with comorbidities, functional impairment, and frailty, limiting eligibility for intensive chemotherapy or allogeneic transplantation. Historically, treatment options were restricted to hypomethylating agents, low‐dose cytarabine, hydroxyurea, or supportive care, with
Antonella Bruzzese +11 more
wiley +1 more source
Correction: TP53-mutated myelodysplastic syndromes and acute myeloid leukemia: a comprehensive overview of targeted approaches. [PDF]
Deshpande S +6 more
europepmc +1 more source
Platelet glycosylation in myelodysplastic syndromes correlates with disease severity. [PDF]
Rosenbalm KE +10 more
europepmc +1 more source

