Results 51 to 60 of about 42,337 (292)

Outcomes of Post‐Transplant Rh‐GCSF and Decitabine Maintenance Therapy in Patients With High‐Risk Myeloid Neoplasm

American Journal of Hematology, EarlyView.
Mathias Palmer, Anmol Baranwal, Rami Basmaci, Khalil Hassan, Jade Kutzke, Gabriel Bartoo, Hemant Murthy, James Foran, Abhishek A. Mangaonkar, Mehrdad Hefazi, Aasiya Matin, William J. Hogan, Mark Litzow, Mithun Vinod Shah, Hassan B. Alkhateeb   +14 more
wiley   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Transforming growth factor β1-mediated functional inhibition of mesenchymal stromal cells in myelodysplastic syndromes and acute myeloid leukemia

Haematologica, 2018
Mesenchymal stromal cells are involved in the pathogenesis of myelodysplastic syndromes and acute myeloid leukemia, but the underlying mechanisms are incompletely understood.
Stefanie Geyh, Manuel Rodríguez-Paredes, Paul Jäger, Annemarie Koch, Felix Bormann, Julian Gutekunst, Christoph Zilkens, Ulrich Germing, Guido Kobbe, Frank Lyko, Rainer Haas, Thomas Schroeder   +11 more
doaj   +1 more source

Expert Perspective: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

A Case of Malignant Melanoma Metastasis in the Ileal Conduit

IJU Case Reports, EarlyView.
ABSTRACT Introduction Tumor development in the ileal conduit is rare. Herein, we present a case of metastatic malignant melanoma occurring within the ileal conduit 17 years after radical cystectomy. Case Presentation A 76‐year‐old Japanese man, with a history of bladder cancer treated with radical cystectomy and ileal conduit diversion, presented with ...
Noritoshi Shamoto, Yushi Naito, Yuta Sano, Kazuna Matsuo, Satoshi Inoue, Tomoyasu Sano, Tomokazu Kimura, Shohei Ishida, Yoshihisa Matsukawa, Shusuke Akamatsu   +9 more
wiley   +1 more source

Clinical activity of azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia

Haematologica, 2016
Disease relapse is the most common cause of treatment failure after allogeneic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndromes, yet treatment options for such patients remain extremely limited.
Charles Craddock, Myriam Labopin, Marie Robin, Juergen Finke, Patrice Chevallier, Ibrahim Yakoub-Agha, Jean Henri Bourhis, Henrik Sengelov, Didier Blaise, Thomas Luft, Michael Hallek, Nicolaus Kröger, Arnon Nagler, Mohamad Mohty   +13 more
doaj   +1 more source

Tandem High‐Dose Chemotherapy and Autologous Stem Cell Transplantation for Osteosarcoma with Initial Pulmonary Metastases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although the survival rates of patients with localized osteosarcoma have significantly improved, metastatic osteosarcoma still has a poor prognosis. The role of high‐dose chemotherapy and autologous stem cell transplantation (HDC/ASCT) in high‐risk osteosarcoma remains unclear compared to that of conventional chemotherapy, and an ...
Hyun Jin Park, Kyung Taek Hong, Jung Yoon Choi, Bo Kyung Kim, Han‐Soo Kim, Samina Park, Sung‐Hye Park, Jung‐Eun Cheon, Hyoung Jin Kang   +8 more
wiley   +1 more source

Familial myelodysplastic syndromes: a review of the literature

Haematologica, 2011
Familial cases of myelodysplastic syndromes are rare, but are immensely valuable for the investigation of the molecular pathogenesis of myelodysplasia in general.
Elena Liew, Carolyn Owen
doaj   +1 more source

Syndecan‐1 is Associated With Sinusoidal Obstruction Syndrome and Severe Acute Graft‐Versus‐Host Disease After Pediatric Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Endothelial damage may play a key role in several non‐infectious toxicities following hematopoietic stem cell transplantation (HSCT). We explored damage to the endothelial glycocalyx in 113 children undergoing HSCT by measuring syndecan‐1 plasma levels.
Denise Elbæk Horan, Sarah Weischendorff, Pär I. Johansson, Marianne Ifversen, Claus H. Nielsen, Klaus Müller, Katrine Kielsen   +6 more
wiley   +1 more source

Recombinant human erythropoietin plus all-trans retinoic acid and testosterone undecanoate for the treatment of anemia in patients with lower-risk myelodysplastic syndromes: a multicenter, single-arm, prospective trial

Haematologica
Erythropoiesis-stimulating agents (ESAs) achieve hematological improvement-erythroid (HIE) in only 30% of ESA-naïve lower risk myelodysplastic syndrome (LR-MDS) patients with anemia, highlighting the need for developing novel drugs or new treatment ...
Chen Mei, Gaixiang Xu, Cuiping Zheng, Yaping Xie, Minming Li, Yanping Shao, Rongxin Yao, Shi Tao, Wei Jiang, Jun Guo, Zhiyin Zheng, Wei Wang, Xinping Zhou, Liya Ma, Li Ye, Yingwan Luo, Chunmei Yang, Wenjuan Yu, Wanzhuo Xie, Jie Jin, Hongyan Tong   +20 more
doaj   +1 more source