Results 91 to 100 of about 23,609 (230)

Bleeding Complications in JAK2‐Variant Essential Thrombocythemia: A Revisit in 2025

eJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterised by sustained thrombocytosis. Paradoxically, bleeding complications remain an under‐recognised clinical challenge. Compared with CALR‐mutated patients, those harbouring the JAK2‐V617F variant appear more prone to haemorrhage.
Gerard Gurumurthy, Samantha Gurumurthy, Tim C. P. Somervaille, Anna Falanga, Jecko Thachil   +4 more
wiley   +1 more source

The pattern and clinical significance of karyotypic abnormalities in patients with idiopathic and postpolycythemic myelofibrosis [PDF]

, 1985
Jonathan Miller, Joseph R. Testa, Valerie Lindgren, Janet D. Rowley   +3 more
openalex   +1 more source

Post‐Diagnosis Hemorrhagic Events Are Strongly Associated With Poor Survival in Patients With Essential Thrombocythemia

eJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Objectives The present study investigated the effects of thrombosis, hemorrhagic events, disease progression, and secondary malignancies on patient survival after the diagnosis of essential thrombocythemia (ET). Methods We analyzed data from 1152 patients enrolled in the JSH‐MPN‐18 study using time‐dependent Cox regression and multistate ...
Yoshinori Hashimoto, Tomoki Ito, Akihiko Gotoh, Mika Nakamae, Fumihiko Kimura, Michiaki Koike, Keita Kirito, Hideho Wada, Kensuke Usuki, Takayuki Tanaka, Takehiko Mori, Satoshi Wakita, Toshiki I. Saito, Akiko Kada, Akiko M. Saito, Kazuya Shimoda, Yuka Sugimoto, Toshiro Kurokawa, Akihiro Tomita, Yoko Edahiro, Hitoshi Kiyoi, Koichi Akashi, Itaru Matsumura, Katsuto Takenaka, Norio Komatsu   +24 more
wiley   +1 more source

Immunologic abnormalities in myelofibrosis with activation of the complement system [PDF]

, 1981
BR Gordon, M Coleman, P Kohen, N K Day
openalex   +1 more source

What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog

Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson, King Long Hannah Lee, Megan Dietz, Sarah Guess, Laura White, Mara S. Varvil   +5 more
wiley   +1 more source

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

Novel approaches in myelofibrosis

HemaSphere
AbstractMyelofibrosis (MF) is a clonal myeloid neoplasm characterized by bone marrow fibrosis, splenomegaly, and disease‐associated symptoms, as well as increased mortality, due to thrombosis, severe bleeding, infections, or progression to acute leukemia.
openaire   +4 more sources

Rituximab for the Management of an Australian Cohort of Treatment Refractory Mucous Membrane Pemphigoid

Australasian Journal of Dermatology, Volume 66, Issue 5, Page e271-e278, August 2025.
ABSTRACT Background Mucous membrane pemphigoid (MMP) has a broad range of clinical manifestations, from relatively benign self‐limiting oral lesions to significant scarring (cicatrizing) of the oral, nasal and ocular tissues with severe functional impairment and morbidity.
Bronte Jeffrey, Mark Schifter, Elizabeth Arena, Emily Sullivan, Stephanie Rose, David Joo, David Campbell, Suzanne Culican, David McDonald, Ming Wei Lin   +9 more
wiley   +1 more source

PROGNOSTIC CLASSIFICATION OF MYELOFIBROSIS WITH MYELOID METAPLASIA [PDF]

, 1989
Giovanni Barosi
openalex   +1 more source

Pathogenic variants in chromatin‐related genes: Linking immune dysregulation to neuroregression and acute neuropsychiatric disorders

Developmental Medicine &Child Neurology, Volume 67, Issue 8, Page 1095-1102, August 2025.
Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 This original article is commented by Thompson on pages 975–976 of this issue. Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐
Russell C. Dale, Shekeeb Mohammad, Velda X. Han, Hiroya Nishida, Himanshu Goel, Stuart G. Tangye, Georgina Hollway, Esther Tantsis, Deepak Gill, Shrujna Patel, Chromatin Immune‐Brain Group, Michael Lonergan, Melanie Wong, Kavitha Kothur, Erica Tsang   +14 more
wiley   +1 more source