Results 21 to 30 of about 27,191 (241)
Haematologica, 2015 Primary myelofibrosis is characterized by clonal myeloproliferation, dysmegakaryopoiesis, extramedullary hematopoiesis associated with myelofibrosis and altered stroma in the bone marrow and spleen.
Christophe Desterke +16 more
doaj +1 more source
Myelofibrosis with myeloid metaplasia (MMM) - Idiopathic myelofibrosis - Agnogenic myeloid metaplasia [PDF]
, 2007 Review on Myelofibrosis with myeloid metaplasia (MMM) - Idiopathic myelofibrosis - Agnogenic myeloid metaplasia, with data on clinics, and the genes ...
Cavazzini, F +3 more
core +1 more source
The Journal of Clinical Investigation, 2022 Myeloproliferative neoplasms (MPNs) are associated with significant alterations in the bone marrow microenvironment that include decreased expression of key niche factors and myelofibrosis. Here, we explored the contribution of TGF-β to these alterations
Juo-Chin Yao +8 more
doaj +1 more source
Сибирский научный медицинский журнал, 2019 The aim of the study was to study the relationship between the qualitative and quantitative characteristics of myelofibrosis and the clinical manifestations of chronic myeloid leukemia and chronic lymphocytic leukemia. Material and methods.
T. Y. Dolgikh +3 more
doaj +1 more source
Primary Myelofibrosis with Mesenteric Extramedullary Haematopoiesis [PDF]
Journal of Clinical and Diagnostic Research, 2018 Primary myelofibrosis or chronic idiopathic myelofibrosis is a myeloproliferative neoplasm characterized by proliferation of abnormal haematopoietic stem cells in bone marrow resulting in replacement of marrow with fibrotic scar tissue.
Saurabh Kumar +4 more
doaj +1 more source
Blood Advances, 2020 Abstract Following the discovery of the JAK2V617F mutation in myeloproliferative neoplasms in 2005, fedratinib was developed as a small molecular inhibitor of JAK2. It was optimized to yield low-nanomolar activity against JAK2 (50% inhibitory concentration = 3 nM) and was identified to be selective for JAK2 relative to other JAK family ...
Ann Mullally +3 more
openaire +2 more sources
Osteolytic lesions in myelofibrosis
, 2021 Bony pain in patients with a history of myelofibrosis warrants further investigation. Although skeletal involvement in myelofibrosis is more commonly osteosclerosis or periostitis, it can also cause osteolytic ...
Hassan Alkhateeb, Isla Johnson
core +1 more source
Haematologica, 2016 Myelofibrosis is a myeloproliferative neoplasm that results in cytopenia, bone marrow fibrosis and extramedullary hematopoiesis. Allogeneic hematopoietic stem cell transplantation is the only curative treatment but is associated with a risk of delayed ...
Christina Hart +8 more
doaj +1 more source
Frontiers in Pediatrics, 2021 Secondary hyperparathyroidism (HPT) is a common complication of end-stage renal disease (ESRD) and may be an important precipitating factor for the development of myelofibrosis.
Keishiro Amano +4 more
doaj +1 more source
Disseminated tuberculosis with myelofibrosis presentation: a case report
Journal of Medical Case Reports, 2021 Background Primary myelofibrosis is a rare myeloproliferative disorder in middle-aged and old adults and should be distinguished from secondary and reactive causes of bone marrow fibrosis because, in reactive fibrosis, treatment approaches depend on the ...
Mahdi Khatuni +3 more
doaj +1 more source