Results 141 to 150 of about 477,278 (318)
Histochemical similarities between newborn and leukaemic myeloid cells and their possible significance [PDF]
, 1969 Paul L. Wolf +4 more
openalex +1 more source
An Overview of Myeloid Blast-Phase Chronic Myeloid Leukemia
CancersMyeloid blast-phase chronic myeloid leukemia (MBP-CML) is a rare disease with a dismal prognosis. It is twice as common as lymphoid blast-phase CML, and its prognosis is poorer. Despite the success with tyrosine kinase inhibitors in the treatment of chronic-phase CML, the same does not hold true for MBP-CML.
Gulsum E. Pamuk, Lori A. Ehrlich
openaire +2 more sources
Advanced Therapeutics, EarlyView.Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi +5 more
wiley +1 more source
Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment
Advanced Therapeutics, EarlyView.How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley +1 more source
Extramedullary myeloid tumors in primary myelofibrosis [PDF]
, 1965 Philip Lieberman +2 more
openalex +1 more source
Advanced Science, EarlyView.Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu +14 more
wiley +1 more source
Chromosome Studies in Chronic Myeloid Leukaemia [PDF]
, 1965 Marshall B. Block
openalex +1 more source
Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Advanced Science, EarlyView.Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk +8 more
wiley +1 more source
Electron Microscope Studies on Normal Human Myeloid Elements [PDF]
, 1964 Robert J. Capone +2 more
openalex +1 more source
Advanced Science, EarlyView.Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song +9 more
wiley +1 more source