Results 101 to 110 of about 301,311 (355)
Subtype-specific 3D genome alteration in acute myeloid leukaemia
Nature, 2022 Jie Xu +28 more
semanticscholar +1 more source
Acute myeloid leukaemia and the immune system: implications for immunotherapy
British Journal of Haematology, 2019 The recognition of the curative potential of the graft‐versus‐leukaemia effect for patients with acute myeloid leukaemia (AML) undergoing stem cell transplantation, and the emergence of immunotherapy as a powerful weapon to treat cancer, has spurred the ...
A. Barrett
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Time Trends and Geographical Distribution of Childhood Leukaemia in Basrah, Iraq,from 2004 to 2009
Sultan Qaboos University Medical Journal, 2011 Objectives: This study aimed to assess the incidence and trend of childhood leukaemia in Basrah. Methods: This was a hospital-based cancer registry study carried out at the Pediatric Oncology Ward, Maternity & Children’s Hospital and other institutes in ...
Laith A Alrudainy +4 more
doaj
CBFA2T3‐GLIS2‐positive acute myeloid leukaemia. A peculiar paediatric entity
British Journal of Haematology, 2018 The scenario of paediatric acute myeloid leukaemia (AML), particularly non‐Down syndrome acute megakaryoblastic leukaemia (non‐DS‐AMKL), has been recently revolutionized by the advent of large‐scale, genomic sequencing technologies.
R. Masetti +3 more
semanticscholar +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail +3 more
wiley +1 more source
Case Reports in Ophthalmological Medicine, 2015 Purpose. To evaluate the efficacy of intravitreal bevacizumab and triamcinolone in the treatment of cystoid macular oedema in a case with chronic myeloid leukaemia on imatinib treatment. Methods.
Eric K. Newcott +3 more
doaj +1 more source
South African Journal of Physiotherapy, 1981 The two major varieties of leukaemia in childhood are acute lymphocytic and acute myeloblastic leukaemia. Subclassification of acute lymphocytic leukaemia has defined groups with a good or poor prognosis and different treatment strategies are employed ...
C. D. Karabus
doaj +1 more source