Results 141 to 150 of about 61,255 (306)

Pleural Infiltration Revealing Post-Essential Thrombocythemia Acute Myeloid Leukaemia. [PDF]

EJHaem
Muron C, Luque Paz D, Copin MC, Orvain C.   +3 more
europepmc   +1 more source

Gene editing of BTK using CRISPR/Cas9 to study drug resistance in acute myeloid leukaemia

, 2019
Melanie Märken
openalex   +1 more source

S154: IMATINIB-RESISTANT CLONES ISOLATED FROM A MODEL OF BLAST CRISIS OF CHRONIC MYELOID LEUKAEMIA DIFFER IN MUTATIONS IN BCR::ABL1 AND OTHER CANCER RELATED GENES AND IN THEIR SENSITIVITY TO BH3-MIMETICS

, 2022
A. Laznicka, N. Curik, Václava Polívková, Jitka Koblihova, P. Burda, Alexandra Dolníková, Eva Pokorná, Cyril Šálek, Hana Klamová, Dana Srbová, P. Klener, Kateřina Machová Poláková   +11 more
openalex   +1 more source

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, Accepted Article.
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Treatment outcomes and prognostic factors in children diagnosed with acute myeloid leukaemia in Uganda. [PDF]

BMC Cancer
Nyeko R, Kruger M, Niyonzima N, Atwiine B, Zungu J, Kambugu JB, Verhulst S, van Heerden J.   +7 more
europepmc   +1 more source

Chronic Myeloid Leukaemia

International Journal of Clinical Practice, 1956
openaire   +2 more sources

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Spinal myeloid sarcoma as a first sign of acute myeloid leukaemia: A case report. [PDF]

Radiol Case Rep
Saliba T, DeLeval L, Blum S, Tsilimidos G, Danthez N, Dunet V.   +5 more
europepmc   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Integrative Bioinformatics Reveals Novel Molecular Mechanisms and Therapeutic Targets in Acute Myeloid Leukaemia. [PDF]

J Cell Mol Med
Daniel MM, Andwey GH.
europepmc   +1 more source