Results 11 to 20 of about 61,255 (306)
Chronic Myeloid Leukaemia in Advanced Phase: An Analytical Evaluation
Journal of Rawalpindi Medical College, 2019 Objective: To evaluate the clinical and morphological features in advanced phase chronic myeloid leukaemia. Methods: This descriptive observational study was conducted at the Pathology Unit of Fauji Foundation Hospital, Rawalpindi from June 2012 till ...
Sehar Khaliq
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Epidemiological characterization of chronic myeloid leukaemia patients at an oncologic centre: A retrospective observational study [PDF]
Hematology, Transfusion and Cell TherapyBackground: The chronic myeloid leukaemia population, treatment patterns and responses in Portugal are unknown. The aim of this study is to describe these features in a Portuguese reference centre.
Ana Maria Meireles +8 more
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The consequences of cohesin mutations in myeloid malignancies
Frontiers in Molecular Biosciences, 2023 Recurrent somatic mutations in the genes encoding the chromatin-regulatory cohesin complex and its modulators occur in a wide range of human malignancies including a high frequency in myeloid neoplasms. The cohesin complex has a ring-like structure which
Shubhra Ashish Bhattacharya +6 more
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Classification of Acute Leukaemia based on Blast Morphology, Cytochemistry and Flow Cytometry [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Acute leukaemias are a heterogeneous group of malignancies due to the abnormal proliferation of immature cells. The classification of acute leukaemia has been transformed over a period.
P Jubit Paulose, J Latha Fathima
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Adult type CML in paediatric age group – a case series from tertiary care hospital
Asian Journal of Medical Sciences, 2021 Chronic myeloid leukaemia is a clonal disorder arising from hematopoietic stem cell, affecting all the lineage of haematopoietic stem cells. The average age of affection in chronic myeloid leukaemia is 60 to 65 years and is extremely rare in childhood ...
Sumaiya Irfan +3 more
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One-year consolidation with Ponatinib 15 mg in chronic myeloid leukaemia on deep molecular response with Imatinib. [PDF]
Ann HematolPérez-Lamas L +20 more
europepmc +3 more sources
Nature Reviews Disease Primers, 2016 Acute myeloid leukaemia (AML) is a disorder characterized by a clonal proliferation derived from primitive haematopoietic stem cells or progenitor cells. Abnormal differentiation of myeloid cells results in a high level of immature malignant cells and fewer differentiated red blood cells, platelets and white blood cells. The disease occurs at all ages,
Khwaja, A +12 more
openaire +4 more sources
Autoimmunity, 2021 Odd-skipped related transcription factor 1 (OSR1) is implicated in various pathophysiologic processes, such as embryonic heart and urogenital formation, and functions as a tumour suppressor in diverse tumours.
Lingyan Zong, Yingxin Sun
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Leukaemic Ascites and Peritoneal Myeloid Sarcoma: Rare but Not Impossible
European Journal of Case Reports in Internal Medicine, 2022 A myeloid sarcoma is an extramedullary tumour arising from infiltration by leukemic cells at an anatomic site other than the bone marrow. Most commonly it precedes acute myeloid leukaemia but occasionally occurs simultaneously.
Luís Landeiro +4 more
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Journal of Translational Medicine, 2022 Background The survival rate for patients with relapsed and refractory acute myeloid leukaemia (R/R-AML) remains poor, and treatment is challenging.
Yu Lu +6 more
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