Results 11 to 20 of about 301,311 (355)
The Lancet, 2023 Progress in acute myeloid leukaemia treatment is occurring at an unprecedented pace. The past decade has witnessed an increasingly improved scientific understanding of the underlying biology of acute myeloid leukaemia, leading to enhanced prognostication tools and refined risk assessments, and most especially incorporating measurable residual disease ...
C. Dinardo, H. Erba, S. Freeman, A. Wei
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The Lancet, 2018 For several decades, few substantial therapeutic advances have been made for patients with acute myeloid leukaemia. However, since 2017 unprecedented growth has been seen in the number of drugs available for the treatment of acute myeloid leukaemia, with several new drugs receiving regulatory approval.
N. Short, M. Rytting, J. Cortes
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Desacetylmethylcolchicine in the Treatment of Myeloid Leukaemia [PDF]
British Journal of Cancer, 1956 A.M. Jelliffe, J. E. MacIver
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Nature Reviews Disease Primers, 2016 Acute myeloid leukaemia (AML) is a disorder characterized by a clonal proliferation derived from primitive haematopoietic stem cells or progenitor cells. Abnormal differentiation of myeloid cells results in a high level of immature malignant cells and fewer differentiated red blood cells, platelets and white blood cells. The disease occurs at all ages,
David A. Scheinberg +12 more
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Spinal Chloroma – Herald of blast crisis in a patient with chronic myeloid leukaemia: A case report
South African Journal of Radiology, 2022 Myeloid sarcoma or chloroma is a localised tumour characterised by extramedullary proliferation of precursor myeloid cells. Commonly occurring in association with acute myeloid leukaemia, chloroma can occasionally be seen in myeloproliferative disorders ...
Stuti Chandola +3 more
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Updates on targeted therapies for acute myeloid leukaemia
British Journal of Haematology, 2021 In the past few years research in the underlying pathogenic mechanisms of acute myeloid leukaemia (AML) has led to remarkable advances in our understanding of the disease.
S. Kayser, M. Levis
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Myeloid Sarcoma Presenting as Nasal and Orbital Mass: An Initial Manifestation of an Acute Myeloid Leukaemia [PDF]
Journal of Clinical and Diagnostic Research, 2017 Myeloid sarcoma is an extramedullary manifestation of Acute Myeloid Leukaemia and sometimes is the only indicator of the disease. The incidence varies between 3-9.1% of acute leukaemia cases.
Amita Jain Gupta +4 more
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Mitochondrial metabolism as a potential therapeutic target in myeloid leukaemia
Leukemia, 2021 While the understanding of the genomic aberrations that underpin chronic and acute myeloid leukaemia (CML and AML) has allowed the development of therapies for these diseases, limitations remain.
Lucie de Beauchamp +2 more
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Nature Communications, 2021 Blast crisis (BC) predicts dismal outcomes in patients with chronic myeloid leukaemia (CML). Although additional genetic alterations play a central role in BC, the landscape and prognostic impact of these alterations remain elusive.
Y. Ochi +34 more
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Egyptian Journal of Medical Human Genetics, 2023 Background Chronic myeloid leukaemia is characterised by genetic instability which results in additional cytogenetic aberrations that have been linked to progression to advanced phase.
Hend Attia, Dina Adel Fouad, Heba Samy
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