Results 181 to 190 of about 212,546 (262)

A mitochondrial-based prognostic score for risk stratification in acute myeloid leukemia. [PDF]

Blood Res
Santos IC, Silva-Xavier VJ, Moreira-Aguiar A, Reis-Silva MT, Silva LP, França-Neto PL, Bezerra MA, Machado-Neto JA, Pereira-Martins DA, Lucena-Araujo AR, Coelho-Silva JL.   +10 more
europepmc   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Apoptosis-related gene model predicts the prognosis in patients with acute myeloid leukemia. [PDF]

Blood Sci
Pei X, Liu W, Li Y, Wei H, Wang M, Wang J.   +5 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Is There a Future for CAR-T Therapy in Acute Myeloid Leukemia? [PDF]

Cancers (Basel)
Alati C, Pitea M, Molica M, Rossi M, Alvaro ME, Porto G, Bilardi E, Utano G, Policastro G, Micò MC, Marafioti V, Martino M.   +11 more
europepmc   +1 more source

Exploring the Value of Quantitative Muscle Ultrasound in Neuromuscular Junction Disorders: A Pilot Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Quantitative muscle ultrasound (QMUS) is a validated technique for assessing muscle pathology, yet its role in disorders primarily affecting the neuromuscular junction (NMJ) remains unclear. This pilot study aimed to explore whether QMUS is associated with structural muscle changes in patients with acquired or genetic NMJ ...
Artor Pogosean, Maarika Liik, Nens van Alfen, Anna Rostedt Punga   +3 more
wiley   +1 more source

Determinants of survival in patients treated with CPX-351 for acute myeloid leukemia. [PDF]

Front Oncol
Chiusolo P, Fianchi L, Frioni F, Giammarco S, Metafuni E, Limongiello MA, Quattrone M, Criscuolo M, Giordano A, Sica S, Pagano L.   +10 more
europepmc   +1 more source

Information Design for Early‐Stage Dose‐Finding Trials

Naval Research Logistics (NRL), EarlyView.
ABSTRACT To enhance enrollment rates in early‐stage dose‐finding clinical trials, we propose an information design approach, where the clinical investigator (CI) commits to an information releasing mechanism (IRM) based on the treatment's uncertain efficacy and toxicity to encourage patients to participate in the trial.
Amin Khademi, Ningyuan Chen
wiley   +1 more source