Results 221 to 230 of about 950,400 (402)

Blastic phase of Ph1-positive chronic myeloid leukemia and t(3;21) [letter] [PDF]

, 1988
Ana Aventín, Cristina Mecucci, Herman Van den Berghe   +2 more
openalex   +1 more source

Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies [PDF]

, 2017
Allegra A. Petti, Amanda M. Smith, Angela M. Verdoni, Catrina Fronick, Celia V. Bangert, Christopher A. Miller, Christopher B. Cole, David A. Russler-Germain, Frith, Gue Su Chang, Jeffery M. Klco, Jeong, Mindy Guo, Nichole M. Helton, Poitras, Robert Fulton, Shamika Ketkar, Shelly O’Laughlin, Timothy J. Ley, Walter, Xi, Zheng   +21 more
core   +2 more sources

Peptidomimetics Targeting the Amyloidogenicity of Nucleophosmin 1 Mutations in Acute Myeloid Leukemia

ChemBioChem, EarlyView.
Previous studies reveal an unexpected tendency for amyloid aggregation in specific regions of the C‐terminal domain (CTD) of nucleophosmin 1 (NPM1), a nucleolar chaperone involved in acute myeloid leukemia (AML). Herein, several peptide analogs of NPM1264‐277 (amyloid core) with conservative substitutions are designed and evaluated through biophysical ...
Daniele Florio, Sara La Manna, Giada Raffaella Fiore, Valentina Roviello, Giuliano Castellano, Sossio Fabio Graziano, Anna Maria Malfitano, Daniela Marasco   +7 more
wiley   +1 more source

High-dose cytosine arabinoside and mitoxantrone: a highly effective regimen in refractory acute myeloid leukemia [PDF]

, 1987
Wolfgang Hiddemann, H. Kreutzmann, Kurt Straíf, WD Ludwig, R Mertelsmann, R Donhuijsen- Ant, Eva Lengfelder, Z Arlin, T Buchner   +8 more
openalex   +1 more source

Chronic myeloid leukemia

HemaSphere, 2019
openaire   +4 more sources

CALR Type 1‐Like Mutations Increase Endoplasmic Reticulum Free Ca2+ and Induce ERK1/2 Activation Independent of Thrombopoietin Receptor Activation

Cell Biology International, EarlyView.
ABSTRACT Calreticulin is a multifunctional protein found in the endoplasmic reticulum lumen that is important for calcium homeostasis and glycoprotein folding. Mutations in exon 9 of the CALR gene are the second most common genetic cause of myeloproliferative neoplasms.
Mifra Faiz, Caitlin Dunstan‐Harrison, Elizabeth C. Ledgerwood   +2 more
wiley   +1 more source

Acute myeloid leukemia with T-lymphoid features: a distinct biologic and clinical entity [PDF]

, 1988
AH Cross, RM Goorha, R Nuss, FG Behm, SB Murphy, DK Kalwinsky, Susana C. Raimondi, GR Kitchingman, J Mirro   +8 more
openalex   +1 more source

Highly Sensitive and Disposable DNA‐Based Electrochemical Biosensor for Detection of Daunorubicin

ChemElectroChem, EarlyView.
Herin, a flower‐like porous MnO2‐modified pencil graphite electrode (MnO2‐PGE) is developed for the electrochemical determination of the anticancer drug daunorubicin and its interaction with dsDNA. The developed electrochemical nanobiosensor has some advantages, such as easy‐to‐handle, cost‐effective, portable, less time‐consuming assay and disposable.
Mukerrem Findik, Keziban Atacan, Emine Guler Akgemci   +2 more
wiley   +1 more source

What Is Acute Myeloid Leukemia? [PDF]

EJHaem
Matos DM, Rego EM.
europepmc   +1 more source

Features of the molecular expression of alkaline phosphatase gene in chronic myeloid leukemia

, 1970
L. P. Shvachko, I. V. Kravchuk, G. D. Teleheiev   +2 more
openalex   +1 more source