Results 241 to 250 of about 467,609 (357)

DHX9 as a prognostic biomarker and its biological roles in acute myeloid leukemia. [PDF]

BMC Cancer
Xiong Y, Chen Y, Luo H, Shi M, Wang C, Hu X, Zhu H.   +6 more
europepmc   +1 more source

Integrated scFv identification and CAR T cell generation for AML targeting in vivo

International Journal of Cancer, EarlyView.
What's New? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu, Annika Lauk, David Sedloev, Josephine Brysting, Ela Cetin, Chunan Liu, Maximilian Mönnig, Thomas Luft, Haiyang Yun, Michael Schmitt, Tim Sauer, Fengbiao Zhou, Christian Rohde, Carsten Müller‐Tidow   +13 more
wiley   +1 more source

Treatment Cessation in Chronic Myeloid Leukemia: Evidence and Uncertainties. [PDF]

Hematol Oncol
Mayer J.
europepmc   +1 more source

Acute myeloid leukemia driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias

Dominic Fowler-Shorten, Rebecca S Maynard, Katherine Hampton, Annalisa Altera, Matthew Markham, Martha Ehikioya, Edyta E. Wojtowicz, Kristian M. Bowles, Stuart A. Rushworth, Charlotte Hellmich   +9 more
openalex   +2 more sources

Oxidative stress induced by the tetrahydrobenzimidazole TMQ0153 modulates crosstalk between apoptosis, autophagy and necroptosis in chronic myeloid leukemia (Part 3 - Figure 4 (b), Figure 5, 6, 7, Supplementary 1-5)

, 2019
Sungmi Song
openalex   +1 more source

Tumor‐infiltrating B cells participate in shaping the immunosuppressive microenvironment in solid tumors

International Journal of Cancer, EarlyView.
Abstract Tumor‐infiltrating B cells (TIBs) exhibit dual roles in the tumor microenvironment (TME) of solid tumors. While they can enhance anti‐tumor immunity through antibody production and immune activation, certain subsets—such as regulatory B cells (Bregs) and immunosuppressive plasma cells—contribute to immune evasion by secreting inhibitory ...
Zhitong Li, Ziyang Shen, Yuxiang Sun, Pengcheng Zhu, Tongyan Liu, Rong Yin   +5 more
wiley   +1 more source

A novel strategy to target metabolic dependencies in acute myeloid leukemia. [PDF]

Cell Death Dis
Balasundaram N, Palani HK, Venkatraman A, Augustin Y, Pichandi S, Regnault C, Solomon M, Rajasekaran A, Yasar M, Palani Kumar S, Radhakrishnan RN, Korula A, Kulkarni UP, Edison ES, Balasubramanian P, George B, Abraham A, Krishna S, Mathews V.   +18 more
europepmc   +1 more source

Intensive chemotherapy after hypomethylating agent and venetoclax in adult acute myeloid leukemia

Kuo‐Kai Chin, Yannis K. Valtis, Andriy Derkach, Meira Yisraeli Salman, Leora Boussi, Jenna Ciervo, Mark B. Geyer, Jae H. Park, Martin S. Tallman, Jacob L. Glass, Aaron D. Goldberg, Eytan M. Stein   +11 more
openalex   +1 more source

Incidence patterns and temporal trends of childhood cancer in Germany, 1980–2019: Forty years of childhood cancer registration in Germany

International Journal of Cancer, EarlyView.
What's New? Childhood cancer ranks among the leading causes of disease‐related deaths in children in high‐income countries. Established risk factors, however, account for only a small proportion of incident childhood cancers. In this report, the authors present the first long‐term assessment of temporal trends in childhood cancer incidence rates in ...
Friederike Erdmann, Maike Wellbrock, Claudia Trübenbach, Desiree Grabow, Martin Schrappe, Peter Kaatsch, Claudia Spix, Joachim Schüz, Cécile M. Ronckers   +8 more
wiley   +1 more source

NIPA1 depletion in tumor-associated macrophages via IGFBP2/EGFR attenuates acute myeloid leukemia progression and chemoresistance. [PDF]

Ann Hematol
Tang S, Sheng L, Mu Q, Wang Y, Chen L, Xu K, Zhou M, Xu Z, Wu A, Ouyang G.   +9 more
europepmc   +1 more source