Results 251 to 260 of about 749,314 (382)

Recombinant human interleukin 6 (B‐cell stimulatory factor 2) is a potent inducer of differentiation of mouse myeloid leukemia cells (M1) [PDF]

open access: bronze, 1988
Chisato Miyaura   +6 more
openalex   +1 more source

Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a Pan‐Degrader

open access: yesChemMedChem, EarlyView.
This study introduced DCAF11 as an E3 ligase for PROTAC‐mediated histone deacetylase (HDAC) degradation. By replacing cereblon with DCAF11 as recruited E3 ligase, a selective HDAC6 degrader (A6) was transformed into pan‐HDAC degraders. The lead compound, 1j (FF2039), potently degraded HDACs from classes I, IIa, and IIb, showing strong antiproliferative
Felix Feller   +5 more
wiley   +1 more source

Therapeutics of acute myeloid leukemia with central nervous system involvement. [PDF]

open access: yesClin Hematol Int
Suárez EU   +5 more
europepmc   +1 more source

The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. [PDF]

open access: green, 1987
Michelle M. Le Beau   +6 more
openalex   +1 more source

Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice [PDF]

open access: bronze, 1984
H G Bedigian   +4 more
openalex   +1 more source

Recent advances of CAR-T cells in acute myeloid leukemia. [PDF]

open access: yesTher Adv Hematol
Deng H   +5 more
europepmc   +1 more source

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