Results 261 to 270 of about 749,314 (382)

Chlorogenic Acid: An In‐Depth Review of Its Effectiveness in Cancer Treatment

open access: yesCancer Nexus, EarlyView.
ABSTRACT Cancer remains a formidable global health challenge. Owing to the unsatisfactory curative effects and severe side effects, it is urgent to explore safer and more effective therapeutic alternatives and drugs. Chlorogenic acid (CGA), a natural polyphenol, has emerged as a promising candidate for cancer therapy due to its multiple functions and ...
Bin Wang   +9 more
wiley   +1 more source

Comprehensive DSRCT multi‐omics analyses unveil CACNA2D2 as a diagnostic hallmark and super‐enhancer‐driven EWSR1::WT1 signature gene

open access: yes
Cancer Communications, EarlyView.
Florian Henning Geyer   +33 more
wiley   +1 more source

Evolving Recommendations for Patient Populations Among Oncology Medicines: A Quantitative and Qualitative Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
After a medicine has been tested in pivotal trials, regulators, health technology assessment (HTA) organizations, and professional societies make decisions about the patients best served by the medicine. This study assesses how the patient populations for oncology medicines (2010–2023) are defined (1) at trial, (2) regulatory submission, (3) upon ...
Milou A. Hogervorst   +5 more
wiley   +1 more source

TimeFlow: A Density‐Driven Pseudotime Method for Flow Cytometry Data Analysis

open access: yesCytometry Part A, EarlyView.
TimeFlow is a new pseudotime computation method for multi‐dimensional flow cytometry data. It orders the cells from the least to most differentiated along their maturation pathway and is useful in modeling the temporal dynamics of surface protein markers along linear trajectories of bone marrow cell populations.
Margarita Liarou   +2 more
wiley   +1 more source

Differentiating reactive and neoplastic gamma‐delta (γδ) T‐cell expansions in the peripheral blood and bone marrow

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract The clinical and immunophenotypic attributes of reactive γδ T‐cell expansions are less well characterized than their malignant counterparts, which can pose diagnostic challenges. This study aims to investigate the characteristics and long‐term clinical outcomes of reactive γδ T‐cell expansions.
Hamza Tariq   +6 more
wiley   +1 more source

Targeting chromatin modifying complexes in acute myeloid leukemia. [PDF]

open access: yesStem Cells Transl Med
Schurer A   +2 more
europepmc   +1 more source

Somatic mutations precede acute myeloid leukemia years before diagnosis

open access: yesNature Network Boston, 2018
Pinkal M. Desai   +11 more
semanticscholar   +1 more source

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